205823-29-6

Basic information

• Product Name: 4-(2-naphthyl)benzoic acid methyl ester
• Synonyms: 4-(2-naphthyl)benzoic acid methyl ester
• CAS NO: 205823-29-6
• Molecular Weight: 262.308
• Mol File: 205823-29-6.mol
• Article Data: 14

Chemical Properties

• CAS DataBase Reference: 4-(2-naphthyl)benzoic acid methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 4-(2-naphthyl)benzoic acid methyl ester(205823-29-6)
• EPA Substance Registry System: 4-(2-naphthyl)benzoic acid methyl ester(205823-29-6)

Safety Data

• Hazardous Substances Data: 205823-29-6(Hazardous Substances Data)

Upstream product

• 905966-40-7 methyl 4-(5,5-dimethyl-1,3,2-dioxaborinan-2-yl)benzoate 
• 115311-03-0 2-(tert-butoxycarbonyloxy)naphthalene 
• 1503-86-2 2-naphthyl pivalate 
• 1145-08-0 naphthalen-2-yl N,N-dimethylsulfamic acid 
• 10290-91-2 naphthalen-2-yl methanesulfonate 
• 61912-14-9 2-naphthyl diethylcarbamate 
• 619-42-1 4-methoxycarbonylphenyl bromide 
• 32316-92-0 naphthalene-2-boronic acid 
• 580-13-2 2-bromonaphthalene 
• 613-46-7 2-naphthalenecarbonitrile 
• 1126-46-1 Methyl 4-chlorobenzoate 
• 91-20-3 naphthalene 
• 619-44-3 methyl 4-iodobenzoate 
• 3857-83-8 2-naphthyl triflate 

Downstream Products

• 106359-62-0 4-(2-naphthyl)phenyl hydroxamic acid 
• 106359-70-0 4-(naphthalen-2-yl)benzoic acid 

Relevant articles and documents

meta-Selective C?H Arylation of Fluoroarenes and Simple Arenes

Fluorine is known to promote ortho-C?H metalation. Based upon this reactivity, we employed an activated norbornene that traps the ortho-palladation intermediate and is then relayed to the meta position, leading to meta-selective C?H arylation of fluoroarenes. Deuterium experiment suggests that this meta-arylation is initiated by ortho C?H activation and the catalytic cycle is terminated by C-2 protonation. A dual-ligand system is crucial for the observed high reactivity and site selectivity. Applying this approach to simple benzene or other arenes also affords arylation products with good yield and site selectivity.

Bathocuproine-Enabled Nickel-Catalyzed Selective Ullmann Cross-Coupling of Two sp 2-Hybridized Organohalides

Cross-coupling reactions are essential for the synthesis of complex organic molecules. Here, we report a nickel-catalyzed Ullmann cross-coupling of two sp 2-hybridized organohalides, featuring high cross-selectivity when the two coupling partners are used in a 1:1 ratio. The high chemoselectivity is governed by the bathocuproine ligand. Moreover, the mild reductive reaction conditions allow that a wide range of functional groups are compatible in this Ullmann cross-coupling.

Decarbonylative Phosphorylation of Carboxylic Acids via Redox-Neutral Palladium Catalysis

We describe the direct synthesis of organophosphorus compounds from ubiquitous aryl and vinyl carboxylic acids via decarbonylative palladium catalysis. The catalytic system shows excellent scope and tolerates a wide range of functional groups (>50 examples). The utility of this powerful methodology is highlighted in the late-stage derivatization directly exploiting the presence of the prevalent carboxylic acid functional group. DFT studies provided insight into the origin of high bond activation selectivity and P(O)-H isomerization pathway.