205878-77-9Relevant articles and documents
Self-assembled oligonucleotide-polyester dendrimers
Goh, Sarah L.,Francis, Matthew B.,Frechet, Jean M. J.
, p. 2954 - 2955 (2002)
A new approach to the controlled synthesis of multicomponent dendrimers is presented, in which three oligonucleotide-dendron conjugates were synthesized using solid phase techniques and hybridized to create a second generation polyester dendrimer with DNA
Degradable self-assembling dendrons for gene delivery: Experimental and theoretical insights into the barriers to cellular uptake
Barnard, Anna,Posocco, Paola,Pricl, Sabrina,Calderon, Marcelo,Haag, Rainer,Hwang, Mark E.,Shum, Victor W. T.,Pack, Daniel W.,Smith, David K.
, p. 20288 - 20300 (2012/02/05)
This paper uses a combined experimental and theoretical approach to gain unique insight into gene delivery. We report the synthesis and investigation of a new family of second-generation dendrons with four triamine surface ligands capable of binding to DN
Designing macromolecules for therapeutic applications: Polyester dendrimer-poly(ethylene oxide) "bow-tie" hybrids with tunable molecular weight and architecture
Gillies, Elizabeth R.,Frechet, Jean M. J.
, p. 14137 - 14146 (2007/10/03)
The design and preparation of new polyester dendrimer, poly(ethylene oxide) hybrid systems for drug delivery and related therapeutic applications, are described. These systems consist of two covalently attached polyester dendrons, where one dendron provid
