20592-20-5 Usage
General Description
13,14-Dihydro Prostaglandin F1alpha is a chemical compound derived from the metabolism of arachidonic acid that exerts various biological effects in the body. It is a prostaglandin, which is a type of lipid-derived hormone that plays a role in inflammation, blood clotting, and other physiological processes. Specifically, 13,14-Dihydro Prostaglandin F1alpha has been found to have vasodilatory properties, meaning it can relax and widen blood vessels, leading to increased blood flow. This property makes it potentially useful in the treatment of conditions such as hypertension, peripheral vascular disease, and certain heart conditions. Additionally, it is also being researched for its potential role in promoting wound healing and tissue repair. Overall, 13,14-Dihydro Prostaglandin F1alpha is a biologically active compound with important physiological implications.
Check Digit Verification of cas no
The CAS Registry Mumber 20592-20-5 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,0,5,9 and 2 respectively; the second part has 2 digits, 2 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 20592-20:
(7*2)+(6*0)+(5*5)+(4*9)+(3*2)+(2*2)+(1*0)=85
85 % 10 = 5
So 20592-20-5 is a valid CAS Registry Number.
20592-20-5Relevant articles and documents
Design and synthesis of 13,14-dihydro prostaglandin F(1α) analogues as potent and selective ligands for the human FP receptor
Wang, Yili,Wos, John A.,Dirr, Michelle J.,Soper, David L.,DeLong, Mitchell A.,Mieling, Glen E.,De, Biswanath,Amburgey, Jack S.,Suchanek, Eric G.,Taylor, Cynthia J.
, p. 945 - 952 (2007/10/03)
The in vitro evaluation of a new class of potential bone anabolic agents for the treatment of osteoporosis is described. These compounds are potent and selective ligands for the human prostaglandin F receptor (hFP receptor). The compounds lack the olefin unsaturation required for potency in the natural ligand PGF(2α) yet retain binding affinity for the hFP receptor in the nanomolar to micromolar range. Removal of the alkenes also results in a better selectivity ratio for the hFP receptor over the other prostaglandin receptors tested. A rationale for the selectivity differences of various analogues, based on ligand docking experiments to a putative hFP receptor model, is also described.
