206265-98-7 Usage
Description
O-(2-AMINOETHYL)-O'-(2-(BOC-AMINO)ETHYL), also known as t-boc-N-amido-PEG7-amine, is a polyethylene glycol (PEG) derivative characterized by its mono-protected homobifunctional structure. O-(2-AMINOETHYL)-O'-(2-(BOC-AMINO)ETHYL) features an amino group and a Boc-protected amino group, with the hydrophilic PEG spacer enhancing solubility in aqueous media. The Boc group can be deprotected under mild acidic conditions, yielding the free amine. The highly purified nature of this compound ensures oligomer purities of more than 90%, which is crucial for achieving homogeneous products in various applications.
Uses
Used in Bioconjugation Applications:
O-(2-AMINOETHYL)-O'-(2-(BOC-AMINO)ETHYL) is used as a reagent for the preparation of biotinylated spacers present in glucose-transporter probes. The PEG linker with an amino group and Boc-protected amino group facilitates the formation of stable and functional bioconjugates, which are essential for various biological and medical applications.
Used in Solubility Enhancement:
In the pharmaceutical industry, O-(2-AMINOETHYL)-O'-(2-(BOC-AMINO)ETHYL) is used as a solubility-enhancing agent for various drug molecules. The hydrophilic PEG spacer increases the solubility of the drug in aqueous media, improving its bioavailability and overall effectiveness.
Used in Drug Delivery Systems:
O-(2-AMINOETHYL)-O'-(2-(BOC-AMINO)ETHYL) is also utilized in the development of drug delivery systems, where it serves as a PEG linker to improve the stability, solubility, and circulation time of drug molecules in the body. This application is particularly relevant in the fields of targeted drug delivery and controlled release formulations.
Used in Chemical Synthesis:
In the field of chemical synthesis, O-(2-AMINOETHYL)-O'-(2-(BOC-AMINO)ETHYL) is employed as a versatile building block for the synthesis of various PEGylated compounds, including PEGylated proteins, peptides, and other bioactive molecules. The Boc-protected amino group allows for selective deprotection and further functionalization under mild conditions, enabling the synthesis of complex PEGylated structures with precise control over molecular architecture.
Check Digit Verification of cas no
The CAS Registry Mumber 206265-98-7 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,0,6,2,6 and 5 respectively; the second part has 2 digits, 9 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 206265-98:
(8*2)+(7*0)+(6*6)+(5*2)+(4*6)+(3*5)+(2*9)+(1*8)=127
127 % 10 = 7
So 206265-98-7 is a valid CAS Registry Number.
InChI:InChI=1/C21H44N2O9/c1-21(2,3)32-20(24)23-5-7-26-9-11-28-13-15-30-17-19-31-18-16-29-14-12-27-10-8-25-6-4-22/h4-19,22H2,1-3H3,(H,23,24)
