206269-27-4

Basic information

• Product Name: 1-[(2S,3S,4S,5S)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1,2,4-triazole-3-carboxamide
• Synonyms: 1-[(2S,3S,4S,5S)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1,2,4-triazole-3-carboxamide;1-[(2S,3S,4R,5S)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1,2,4-triazole-3-carboxamide;1-[(2S,3S,4R,5S)-3,4-dihydroxy-5-methylol-tetrahydrofuran-2-yl]-1,2,4-triazole-3-carboxamide
• CAS NO: 206269-27-4
• Molecular Formula: C₈H₁₂N₄O₅
• Molecular Weight: 244.2
• Product Categories: Anti-virals, Nucleotides, Bases & Related Reagents, Pharmaceuticals, Intermediates & Fine Chemicals
• Mol File: 206269-27-4.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 639.8°Cat760mmHg
• Flash Point: 340.7°C
• Appearance: /
• Density: 2.08g/cm³
• Vapor Pressure: 3.03E-17mmHg at 25°C
• Refractive Index: 1.823
• CAS DataBase Reference: 1-[(2S,3S,4S,5S)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1,2,4-triazole-3-carboxamide(CAS DataBase Reference)
• NIST Chemistry Reference: 1-[(2S,3S,4S,5S)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1,2,4-triazole-3-carboxamide(206269-27-4)
• EPA Substance Registry System: 1-[(2S,3S,4S,5S)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1,2,4-triazole-3-carboxamide(206269-27-4)

Safety Data

• Hazardous Substances Data: 206269-27-4(Hazardous Substances Data)

Usage

Description

1-[(2S,3S,4S,5S)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1,2,4-triazole-3-carboxamide is a complex organic compound with a unique molecular structure. It is characterized by its stereochemistry, with four stereocenters in the 2S, 3S, 4S, and 5S configurations. The molecule contains a triazole ring and a carboxyamide group, which may contribute to its potential biological activities.

Uses

1. Used in Pharmaceutical Applications:
1-[(2S,3S,4S,5S)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1,2,4-triazole-3-carboxamide is used as a pharmaceutical compound for its potential immunomodulatory and therapeutic properties. The specific application reason is due to its structural features that may allow it to interact with biological targets and modulate immune responses.
2. Used in Drug Delivery Systems:
In the field of drug delivery, 1-[(2S,3S,4S,5S)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1,2,4-triazole-3-carboxamide may be utilized as a component in the design of novel drug delivery systems. Its unique structure could be exploited to enhance the delivery, bioavailability, and therapeutic outcomes of various drugs, particularly in the context of targeted therapies.
3. Used in Chemical Synthesis:
1-[(2S,3S,4S,5S)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1,2,4-triazole-3-carboxamide can also be used as a synthetic building block in the development of new chemical entities. Its versatile structure may serve as a starting point for the synthesis of various bioactive molecules, potentially leading to the discovery of new drugs and therapeutic agents.

InChI:InChI=1/C8H12N4O5/c9-6(16)7-10-2-12(11-7)8-5(15)4(14)3(1-13)17-8/h2-5,8,13-15H,1H2,(H2,9,16)/t3-,4-,5-,8-/m0/s1

Upstream product

• 206269-26-3 methyl 1-(2,3,5-tri-O-acetyl-β-L-ribofuranosyl)-1,2,4-triazole-3-carboxylate 
• 41546-21-8 L-ribose 
• 144490-03-9 1,2,3,5-tetra-O-acetyl-β-L-ribofuranose 

Downstream Products

• 263708-22-1 1-[2-O-phenylthioformate-3,5-O-(1,1,3,3-tetraisopropyl-1,3-O-disiloxanyl)-β-L-ribofuranosyl]-1,2,4-triazole-3-carboxamide 
• 705929-70-0 1-(6S-hydroxymethyl-2-phenyl-tetrahydro-3aS,6aS-furo[3,4-d][1,3]dioxol-4S-yl)-1H-[1,2,4]triazole-3-carboxylic acid amide 
• 705930-01-4 2S-benzyloxycarbonylamino-3-methyl-butyric acid 5S-(3-carbamoyl-[1,2,4]triazol-1-yl)-3R,4S-dihydroxy-tetrahydro-furan-2S-ylmethyl ester 

Relevant articles and documents

Monocyclic L-nucleosides, analogs and uses thereof

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