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206548-14-3

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206548-14-3 Usage

General Description

Methyl 2-amino-5-bromo-3-methylbenzenecarboxylate, also known as CAS No. 70274-51-4, is an organic chemical compound belonging to the class of organic compounds known as benzoic acid esters. Its molecular formula is C9H10BrNO2. It is characterized by the presence of a bromo substituent along with two methyl groups attached to different positions of a benzene ring. It has a role as a synthetic compound used for chemical synthesis and research purposes. Its other properties, such as solubility, stability, melting and boiling points, may vary according to environmental conditions and purity of the sample. Chemical handling and disposal should be done according to prescribed regulations due to its potential hazards.

Check Digit Verification of cas no

The CAS Registry Mumber 206548-14-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,0,6,5,4 and 8 respectively; the second part has 2 digits, 1 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 206548-14:
(8*2)+(7*0)+(6*6)+(5*5)+(4*4)+(3*8)+(2*1)+(1*4)=123
123 % 10 = 3
So 206548-14-3 is a valid CAS Registry Number.

206548-14-3SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 12, 2017

Revision Date: Aug 12, 2017

1.Identification

1.1 GHS Product identifier

Product name methyl 2-amino-5-bromo-3-methylbenzoate

1.2 Other means of identification

Product number -
Other names 2-Amino-5-bromo-3-methyl-benzoic acid methyl ester

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:206548-14-3 SDS

206548-14-3Relevant articles and documents

Rational design of selective inhibitors of PARP4

Cohen, Michael,Kirby, Ilsa T.,Person, Ashley

, p. 1950 - 1957 (2021/12/24)

PARPs (PARP1-16 in humans) are a large family of ADP-ribosyltransferases (ARTs) that have diverse roles in cellular physiology and pathophysiology. Most PARP family members mediate mono-ADP-ribosylation (MARylation) of targets. The function of PARP-mediated MARylation in cells is poorly characterized, due in large part to the paucity of selective small molecule inhibitors of the catalytic activity of individual PARP enzymes. Herein we describe the rational design of selective small molecule inhibitors of PARP4 (also known as vPARP). These inhibitors are based on a quinazolin-4(3H)-one scaffold, and contain substituents at the C-8 position designed to exploit a unique threonine (Thr484, human PARP4 numbering) in the PARP4 nicotinamide sub-pocket. Our most potent analog, AEP07, which contains an iodine at the C-8 position, is at least 12-fold selective over other PARP family members. AEP07 will serve as a useful lead compound for the further development of PARP4 inhibitors that can be used to probe the cellular functions of PARP4 catalytic activity. This journal is

ARYL, HETEROARY, AND HETEROCYCLIC PHARMACEUTICAL COMPOUNDS FOR TREATMENT OF MEDICAL DISORDERS

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Page/Page column 474; 475, (2018/09/21)

Complement Factor D inhibitors, pharmaceutical compositions, and uses thereof, as well as processes for their manufacture are provided. The compounds provided include Formula I, Formula II, Formula III, Formula IV, and Formula V, or a pharmaceutically acceptable salt, prodrug, isotopic analog, N-oxide, or isolated isomer thereof, optionally in a pharmaceutically acceptable composition. The inhibitors described herein target Factor D and inhibit or regulate the complement cascade.

POLYSUBSTITUTED PYRIDYL PYRAZOLECARBOXAMIDE AND PREPARATION METHOD AND USE THEREOF

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Paragraph 0052; 0053; 0054, (2015/11/28)

The present invention discloses a polysubstituted pyridyl pyrazolecarboxamide and its preparation method and use. The structure of the polysubstituted pyridyl pyrazolecarboxamide of the present invention is shown in the following General Formula I. The po

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