206660-42-6 Usage
Description
(2R)-Pinocembrin, also known as the (R)-enantiomer of Pinocembrin, is a flavanoid with antioxidant activity found in natural sources such as damiana, honey, and propolis. It is a promising compound due to its potential inhibitory effects on PIM1 kinase, an oncogene implicated in the development of leukemias, lymphomas, and prostate cancer.
Uses
Used in Pharmaceutical Industry:
(2R)-Pinocembrin is used as a potential therapeutic agent for the treatment of various cancers, including leukemias, lymphomas, and prostate cancer. Its ability to inhibit PIM1 kinase makes it a valuable candidate for cancer research and drug development.
Used in Antioxidant Applications:
(2R)-Pinocembrin is used as an antioxidant due to its presence in natural sources like honey and propolis. Its antioxidant properties can help protect cells from damage caused by free radicals and oxidative stress, contributing to overall health and well-being.
Check Digit Verification of cas no
The CAS Registry Mumber 206660-42-6 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,0,6,6,6 and 0 respectively; the second part has 2 digits, 4 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 206660-42:
(8*2)+(7*0)+(6*6)+(5*6)+(4*6)+(3*0)+(2*4)+(1*2)=116
116 % 10 = 6
So 206660-42-6 is a valid CAS Registry Number.
206660-42-6Relevant articles and documents
Bioactivity-guided isolation of antiproliferative compounds from Centaurea carduiformis DC
Sahin Yaglioglu, Ayse,Demirtas, Ibrahim,Goren, Nezhun
, p. 213 - 219 (2014)
In this study, antiproliferative activity of methanol extract of Centaura carduiformis DC. subsp. carduiformis var. carduiformis DC (CC) was examined against Vero, HeLa and C6 cell lines in 1000 and 500 μg/mL concentrations using the BrdU ELISA assay. The
METHOD FOR RESOLUTION OF A MIXTURE OF PINOCEMBRIN OPTICAL ISOMERS, ESPECIALLY A PINOCEMBRIN RACEMATE
-
Page/Page column 4, (2010/11/03)
The present invention relates to a method for resolution of a mixture of pinocembrin optical isomers, in particular a pinocembrin racemate, using a chiral primary amine or a chiral sulfinamide. The present invention also relates to a (R)-(+)-pinocembrin obtained by the method.
