20672-18-8

Basic information

• Product Name: 2-(2-PHENYLHYDRAZONO)ACETALDEHYDE
• Synonyms: ETHANEDIAL 1-(N-PHENYLHYDRAZONE);2-(2-PHENYLHYDRAZONO)ACETALDEHYDE
• CAS NO: 20672-18-8
• Molecular Formula: C₈H₈N₂O
• Molecular Weight: 148.16
• Mol File: 20672-18-8.mol
• Article Data: 10

Chemical Properties

• Melting Point: 101.5 °C
• Appearance: /
• CAS DataBase Reference: 2-(2-PHENYLHYDRAZONO)ACETALDEHYDE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(2-PHENYLHYDRAZONO)ACETALDEHYDE(20672-18-8)
• EPA Substance Registry System: 2-(2-PHENYLHYDRAZONO)ACETALDEHYDE(20672-18-8)

Safety Data

• Hazardous Substances Data: 20672-18-8(Hazardous Substances Data)

Usage

Functional groups

Hydrazone and aldehyde

Uses in organic synthesis

Commonly used as a reagent to form hydrazones with carbonyl compounds, which is a key reaction in the formation of Schiff bases

Pharmacological properties

Studied for potential antimicrobial, antioxidant, and anti-inflammatory activities

Fields of use

Chemistry and pharmacology

Upstream product

• 496-45-7 glyoxal sulfate 
• 131543-46-9 Glyoxal 
• 100-63-0 phenylhydrazine 
• 59-88-1 phenylhydrazine hydrochloride 

Downstream Products

• 56139-49-2 1-<2-(Phenylhydrazono)ethyliden>-inden 
• 81429-29-0 (phenylimino)acetaldehyde phenylhydrazone 
• 56139-44-7 1-(4-Methoxy)-4-phenylhydrazono-2-buten-1-on 
• 95884-25-6 4-Hydroxy-1-phenyl-1H-pyrazole-3-carbaldehyde 
• 95884-27-8 4-Hydroxy-1,5-diphenyl-1H-pyrazole-3-carbaldehyde 
• 72430-86-5 (2-Methoxy-phenyl)-[2-(phenyl-hydrazono)-eth-(E)-ylidene]-amine 
• 72430-81-0 [2-(Phenyl-hydrazono)-eth-(E)-ylidene]-p-tolyl-amine 
• 72430-87-6 (4-Chloro-phenyl)-[2-(phenyl-hydrazono)-eth-(E)-ylidene]-amine 
• 75119-88-9 1-{4-[2-(Phenyl-hydrazono)-eth-(E)-ylideneamino]-phenyl}-ethanone 
• 72430-85-4 (4-Methoxy-phenyl)-[2-(phenyl-hydrazono)-eth-(E)-ylidene]-amine 
• 78797-14-5 glyoxal 2-phenylhydrazone thiosemicarbazone 
• 75119-89-0 4-[2-(Phenyl-hydrazono)-eth-(E)-ylideneamino]-benzenesulfonamide 
• 74660-73-4 (ethylenedinitrilo)bisacetaldehyde bisphenylhydrazone 
• 86634-77-7 (trimethylenedinitrilo)bisacetaldehyde bisphenylhydrazone 

Relevant articles and documents

Synthesis of 2-Substituted 1,2,3-Triazoles via an Intramolecular N–N Bond Formation

An efficient synthesis of 2-aryl 1,2,3-triazoles based on an intramolecular N–N bond formation is described. Selective activation of bis-hydrazone at the dimethylamino hydrazone group with MeI forms a mono-hydrazonium species. Treatment of the hydrazonium

Pyrrolo[3,4-c]pyrazole Synthesis via Copper(?) Chloride-Catalyzed Oxidative Coupling of Hydrazones to Maleimides

A variety of pyrrolo[3,4-c]pyrazole derivatives from readily available aldehyde hydrazones and maleimides via direct oxidative coupling under radical cascade reaction have been reported. This method offers satisfactory chemical yields and good functional

Molybdenum-Catalyzed Deoxygenation of Heteroaromatic N-Oxides and Hydroxides using Pinacol as Reducing Agent

A molybdenum-catalyzed deoxygenation of pyridine N-oxides and N-hydroxybenzotriazoles, as well as other azole N-oxides, has been developed using pinacol as an environmentally friendly oxo-acceptor. The only by-products are acetone and water making the process a convenient alternative to established protocols in terms of waste generation. The reaction is highly chemoselective and a variety of functional groups are tolerated. The processes are usually very clean allowing the isolation of the pure deoxygenated products after a simple extraction in most cases. (Figure presented.).