206761-87-7 Usage
Description
1-(2-PIPERIDINOETHYL)-2-THIOUREA is an organic compound with the molecular formula C7H16N2S. It is a derivative of thiourea, featuring a piperidinoethyl group attached to the first nitrogen atom. 1-(2-PIPERIDINOETHYL)-2-THIOUREA is known for its potential applications in the pharmaceutical and chemical industries due to its unique structural properties.
Uses
1. Used in Pharmaceutical Research:
1-(2-PIPERIDINOETHYL)-2-THIOUREA is used as a reagent for studying the antitumor activity of oridonin analogs containing a thiazole-fused A ring. Its role in this context is to help researchers understand the structure-activity relationship of these compounds and potentially develop more effective anti-cancer drugs.
2. Used in Chemical Synthesis:
As a derivative of thiourea, 1-(2-PIPERIDINOETHYL)-2-THIOUREA may also find applications in the synthesis of various organic compounds, particularly those with potential pharmaceutical or chemical uses. Its unique structural features can be exploited to create novel molecules with desired properties.
Check Digit Verification of cas no
The CAS Registry Mumber 206761-87-7 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,0,6,7,6 and 1 respectively; the second part has 2 digits, 8 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 206761-87:
(8*2)+(7*0)+(6*6)+(5*7)+(4*6)+(3*1)+(2*8)+(1*7)=137
137 % 10 = 7
So 206761-87-7 is a valid CAS Registry Number.
InChI:InChI=1/C8H17N3S/c9-8(12)10-4-7-11-5-2-1-3-6-11/h1-7H2,(H3,9,10,12)
206761-87-7Relevant articles and documents
Synthesis of thiophene-2-carboxamidines containing 2-aminothiazoles and their biological evaluation as urokinase inhibitors
Wilson, Kenneth J.,Illig, Carl R.,Subasinghe, Nalin,Hoffman, James B.,Jonathan Rudolph,Soll, Richard,Molloy, Christopher J.,Bone, Roger,Green, David,Randall, Troy,Zhang, Marie,Lewandowski, Frank A.,Zhou, Zhao,Sharp, Celia,Maguire, Diane,Grasberger, Bruce,DesJarlais, Renee L.,Spurlino, John
, p. 915 - 918 (2001)
The serine protease urokinase (uPa) has been implicated in the progression of both breast and prostate cancer. Utilizing structure based design, the synthesis of a series of substituted 4-[2-amino-1,3-thiazolyl]-thiophene-2-carboxamidines is described. Further optimization of this series by substitution of the terminal amine yielded urokinase inhibitors with excellent activities.
