20680-01-7

Basic information

• Product Name: 1-(4-hydroxyphenyl)-3-prop-2-en-1-ylthiourea
• Synonyms: 1-Allyl-3-(4-hydroxyphenyl)thiourea; thiourea, N-(4-hydroxyphenyl)-N'-2-propen-1-yl-
• CAS NO: 20680-01-7
• Molecular Formula: C₁₀H₁₂N₂OS
• Molecular Weight: 208.2801
• Mol File: 20680-01-7.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 340.9°C at 760 mmHg
• Flash Point: 160°C
• Density: 1.256g/cm³
• Vapor Pressure: 4.22E-05mmHg at 25°C
• Refractive Index: 1.674
• CAS DataBase Reference: 1-(4-hydroxyphenyl)-3-prop-2-en-1-ylthiourea(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(4-hydroxyphenyl)-3-prop-2-en-1-ylthiourea(20680-01-7)
• EPA Substance Registry System: 1-(4-hydroxyphenyl)-3-prop-2-en-1-ylthiourea(20680-01-7)

Safety Data

• Hazardous Substances Data: 20680-01-7(Hazardous Substances Data)

Usage

Functional groups

Thiourea derivative, hydroxyphenyl group, prop-2-en-1-yl group

Chemical structure

Contains a nitrogen atom with two substituents (hydroxyphenyl and prop-2-en-1-yl groups)

Potential pharmaceutical applications

Antioxidant, anti-inflammatory, and anticancer properties

Interaction with biological systems

Ability to interact with biological systems due to its functional groups

Drug discovery and development

Subject of interest in drug discovery and development

Chemical modifications and derivatization

Suitable for further chemical modifications and derivatization to enhance activity and selectivity for specific therapeutic applications

Upstream product

• 123-30-8 4-amino-phenol 
• 57-06-7 N-allyl isothiocyanate 

Downstream Products

• 1330061-48-7 4-(3-allylthioureido)phenyl sulfamate 
• 328106-79-2 3-allyl-2-(p-hydroxyphenylimino)-4-phenyl-3H-thiazole 

Relevant articles and documents

Synthesis of new thioureas derivatives and evaluation of their efficacy as proliferation inhibitors in mcf-7 breast cancer cells by using99m tc-mibi radiotracer

Background & Objective: Anti-tumor activity of some thioureas derivatives is well documented in literature and received considerable attention. The present study aims to synthesize and characterize some novel thioureas and carbonylthioureas as anti-tumor

Regioselective synthesis of novel 3-allyl-2-(substituted imino)-4-phenyl-3H-thiazole and 2,2′-(1,3-phenylene)bis(3-substituted-2- imino-4-phenyl-3H-thiazole) derivatives as antibacterial agents

Several novel 3-allyl-2-(substituted imino)-4-phenyl-3H-thiazole derivatives were synthesized by the reaction of allyl-thioureas and 2-bromoacetophenone. We also report the synthesis of bis-allyl-3H thiazoles using the reaction of various isothiocyanates