20684-76-8 Usage
Description
(MORPHOLINOMETHYL)DIPHENYLPHOSPHINE OXIDE, also known as a chemical compound, is commonly utilized as a catalyst in a wide range of organic reactions. This white crystalline solid possesses a molecular formula of C19H21NO2P and a molar mass of 323.34 g/mol. Characterized by its unique structure that includes a morpholine group and a diphenylphosphine oxide group attached to the same carbon atom, it serves as a versatile chemical for organic synthesis. Furthermore, it holds potential applications in medicinal chemistry and acts as a ligand in metal-catalyzed reactions. Recognized for its relative stability and low toxicity, (MORPHOLINOMETHYL)DIPHENYLPHOSPHINE OXIDE emerges as a safer alternative when compared to certain other phosphorus compounds.
Usage:
Used in Organic Synthesis:
(MORPHOLINOMETHYL)DIPHENYLPHOSPHINE OXIDE is used as a catalyst for facilitating various organic reactions, including hydrogenation and polymerization processes. Its unique structure allows it to effectively accelerate these reactions, enhancing the efficiency and yield of the desired products.
Used in Medicinal Chemistry:
In the field of medicinal chemistry, (MORPHOLINOMETHYL)DIPHENYLPHOSPHINE OXIDE serves as a valuable compound due to its potential applications in the development of new pharmaceuticals. Its unique structure and reactivity make it a promising candidate for the synthesis of novel drug molecules.
Used as a Ligand in Metal-Catalyzed Reactions:
(MORPHOLINOMETHYL)DIPHENYLPHOSPHINE OXIDE is also used as a ligand in metal-catalyzed reactions, where it plays a crucial role in enhancing the selectivity and activity of the catalyst. This application is particularly relevant in the synthesis of complex organic molecules and the development of new catalytic processes.
Used in the Chemical Industry:
Within the chemical industry, (MORPHOLINOMETHYL)DIPHENYLPHOSPHINE OXIDE is employed as a catalyst to improve the efficiency of various chemical processes. Its stability and low toxicity make it a preferred choice for industrial applications where safety and environmental concerns are paramount.
Check Digit Verification of cas no
The CAS Registry Mumber 20684-76-8 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,0,6,8 and 4 respectively; the second part has 2 digits, 7 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 20684-76:
(7*2)+(6*0)+(5*6)+(4*8)+(3*4)+(2*7)+(1*6)=108
108 % 10 = 8
So 20684-76-8 is a valid CAS Registry Number.
20684-76-8Relevant articles and documents
8-chloro-1-cyclopropyl-7-fluoro-9-methyl-4-oxo-4-hydroxy-quinolizine-3-carboxylate and synthetic method thereof
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Paragraph 0035; 0036, (2017/08/28)
The invention provides 8-chloro-1-cyclopropyl-7-fluoro-9-methyl-4-oxo-4-hydroxy-quinolizine-3-carboxylate and a synthetic method thereof. The synthetic method comprises the following steps: a compound 6 and tert-butyldimethylsilyl chloride react in a firs
Copper-catalyzed α-amination of phosphonates and phosphine oxides: A direct approach to α-amino phosphonic acids and derivatives
McDonald, Stacey L.,Wang, Qiu
supporting information, p. 1867 - 1871 (2014/03/21)
A direct approach to important α-amino phosphonic acids and its derivatives has been developed by using copper-catalyzed electrophilic amination of α-phosphonate zincates with O-acyl hydroxylamines. This amination provides the first example of C=N bond formation which directly introduces acyclic and cyclic amines to the α-position of phosphonates in one step. The reaction is readily promoted at room temperature with as little as 0.5 mol % of catalyst, and demonstrates high efficiency on a broad substrate scope. A direct approach to important α-amino phosphonic acids and derivatives, by using copper-catalyzed electrophilic amination of α-phosphonate zincates using O-acylhydroxylamines, is described. This amination is the first example of C=N bond formation which directly introduces acyclic and cyclic amines to the α-position of phosphonates in one step. The reaction proceeds at room temperature with as little as 0.5 mol % of the catalyst. Copyright
A New Access to 3-(2'-Aminovinyl)indoles and Their First Diels-Alder Reactions
Pindur, Ulf,Otto, Christian
, p. 403 - 406 (2007/10/02)
3-Acylindoles react with α-amino-α'-diphenylphosphinoyl-substituted carboanions to 3-(2'-aminovinyl)indoles (7 and 12) via carbinols.The electron-rich 3-vinylindoles 7 and 12 undergo Diels-Alder reactions with N-phenylmaleimide.
