20686-91-3

Basic information

• Product Name: Propane-1,3-di(sulfonyl chloride)
• Synonyms: Propane-1,3-di(sulfonyl chloride);Propane-1,3-disulfonyl dichloride
• CAS NO: 20686-91-3
• Molecular Formula: C₃H₆Cl₂O₄S₂
• Molecular Weight: 241.11
• Mol File: 20686-91-3.mol
• Article Data: 6

Chemical Properties

• Boiling Point: 325.5°C at 760 mmHg
• Flash Point: 150.6°C
• Appearance: /
• Density: 1.687g/cm³
• Vapor Pressure: 0.000436mmHg at 25°C
• Refractive Index: 1.517
• CAS DataBase Reference: Propane-1,3-di(sulfonyl chloride)(CAS DataBase Reference)
• NIST Chemistry Reference: Propane-1,3-di(sulfonyl chloride)(20686-91-3)
• EPA Substance Registry System: Propane-1,3-di(sulfonyl chloride)(20686-91-3)

Safety Data

• Hazardous Substances Data: 20686-91-3(Hazardous Substances Data)

Usage

InChI:InChI=1/C3H6Cl2O4S2/c4-10(6,7)2-1-3-11(5,8)9/h1-3H2

Upstream product

• 74-98-6 propane 
• 7314-74-1 1,3-bis(thiocyanato)propane 
• 873396-35-1 2,6-dithia-heptanedioic acid diamide 
• 98957-83-6 1,3-bis-carbamimidoylmercapto-propane; diacetate 
• 109-64-8 1,3-dibromo-propane 
• 21668-77-9 propane-1,3-disulfonic acid 
• 56-23-5 tetrachloromethane 
• 7782-50-5 chlorine 
• 36589-58-9 sodium α,ω-alkanedisulfonate 
• 82203-69-8 barium 1,3-propanedisulfonate 
• 109-80-8 1.3-propanedithiol 
• 5442-32-0 propane‐1,3‐diyl dicarbamimidothioate dihydrobromide 

Downstream Products

• 19218-16-7 1,3-bis-(aziridine-1-sulfonyl)-propane 
• 857193-27-2 propane-1,3-disulfonic acid bis-(4-nitro-phenyl ester) 
• 100976-92-9 propane-1,3-disulfonic acid diphenyl ester 
• 21668-77-9 propane-1,3-disulfonic acid 
• 500878-52-4 N,N'-diphenyl-propane-1,3-disulfonamide 
• 23316-11-2 propane-1,3-disulfonic acid bis-(N'-phenyl-hydrazide) 
• 6274-90-4 Propandisulfonsaeure-(1,3)-dimethylester 
• 101864-25-9 Propandisulfonsaeure-(1,3)-bis-<2,5-dimethyl-phenylester> 
• 16427-45-5 diethyl 1,3-propanedisulfonate 
• 66725-58-4 N-{4-[3-(4-Acetylamino-phenylsulfamoyl)-propane-1-sulfonylamino]-phenyl}-acetamide 
• 1266342-27-1 3-phenoxysulfonyl-1-propanesulfonyl chloride 
• 1309865-50-6 C₂₂H₃₅ClN₂O₈S₂ 
• 1266342-57-7 C₄₁H₆₄N₄O₁₂S₂ 
• 1266342-64-6 1,3-propanedisulfonic acid bis(4-(N-CBz-L-valinamido)-2,2-dimethyl-1-butyl) ester 

Relevant articles and documents

A comparative study of the electrochemical fluorination (ECF) of 1 ,n-alkanebis (sulfonylfluorides) (n = 1-3 )

Synthetic methods for the preparation of α,ω-alkanebis(sulfonylfluorides) and their electrochemical fluorination (ECF) are described in detail. Factors affecting the yield of the perfluoro-α,ω-alkanebis(sulfonylfluorides) are also discussed. Spectral data (13C and 19F NMR and mass spectra) and other hitherto unknown physical properties of difluoromethanebis(sulfonylfluoride) (1), 1,1,2,2-tetrafluoroethane-1,2-bis(sulfonylfluoride) (2) and 1,1,2,2,3,3-hexafluoropropane-1,3-bis(sulfonylfluoride) (3) are measured and compared. Elsevier Science S.A.

Clean and economic synthesis of alkanesulfonyl chlorides from S-alkyl isothiourea salts via bleach oxidative chlorosulfonation

A simple procedure for clean and economic synthesis of alkanesulfonyl chlorides via bleach-mediated oxidative chlorosulfonation of S-alkyl isothiourea salts is disclosed. This procedure is environment- and worker-friendly with the advantages of readily accessible materials and reagents, simple and safe operations, easy purification without chromatography, and affords high yields of up to 99%.

METHODS, COMPOUNDS, AND COMPOSITIONS FOR DELIVERING 1,3-PROPAN ED ISULFONIC ACID

The invention relates to methods, compounds, and compositions for delivering 1,3-propanedisulfonic acid (1,3PDS) in a subject, preferably a human subject. The invention encompasses compounds that will yield or generate 1,3PDS, either in vitro or in vivo. The invention also relates to sulfonate ester prodrugs of 1,3PDS as well as Gemini dimmers and oligomers of 1,3PDS for the prevention or treatment of associated diseases and conditions.