207238-21-9

Basic information

• Product Name: Carbonic acid 2,3-dichloro-phenyl ester ethyl ester
• Synonyms: Carbonic acid 2,3-dichloro-phenyl ester ethyl ester
• CAS NO: 207238-21-9
• Molecular Weight: 235.067
• Mol File: 207238-21-9.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: Carbonic acid 2,3-dichloro-phenyl ester ethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Carbonic acid 2,3-dichloro-phenyl ester ethyl ester(207238-21-9)
• EPA Substance Registry System: Carbonic acid 2,3-dichloro-phenyl ester ethyl ester(207238-21-9)

Safety Data

• Hazardous Substances Data: 207238-21-9(Hazardous Substances Data)

Upstream product

• 576-24-9 2,3-dichlorophenol 
• 541-41-3 chloroformic acid ethyl ester 

Downstream Products

• 173456-54-7 1-(4-benzyloxy-2,3-dichlorophenyl)piperazine 
• 173456-48-9 7-{4-[4-(4-Benzyloxy-2,3-dichloro-phenyl)-piperazin-1-yl]-butoxy}-3,4-dihydro-1H-quinolin-2-one 
• 173456-52-5 2,3-dichloro-4-benzyloxynitrobenzene 
• 173456-53-6 4-(benzyloxy)-2,3-dichloroaniline 
• 59384-57-5 4-nitro-2,3-dichlorophenol 
• 28165-60-8 2,3-dichloro-6-nitrophenol 

Relevant articles and documents

Practical application of the palladium-catalyzed amination in phenylpiperazine synthesis: An efficient synthesis of a metabolite of the antipsychotic agent aripiprazole

A metabolite of Aripiprazole (1), 7-[4-[4-(2,3-dichloro-4- hydroxyphenyl)-1-piperaziyl]butoxy]-3,4-dihydro-2(1H)-quinolinone (2), was prepared by the coupling reaction of 1-(4-benzyloxy-2,3-dichlorophenyl) piperazine (11) with 7-(4-chlorobutoxy)-3,4-dihydro-2(1H)-quinolinone (16). The palladium-catalyzed amination of contiguous tri- and tetra-substituted benzenes with piperazine derivatives was investigated. The key intermediate 11 was efficiently prepared using the palladium-catalyzed amination of phenyl bromide 15 with piperazine.