20731-70-8 Usage
Type of compound
psychoactive and hallucinogenic
Chemical class
tryptamines
Structural similarity
similar to serotonin (a neurotransmitter involved in mood, sleep, and appetite regulation)
Effects
visual and auditory hallucinations, altered perception of time and space, changes in mood and cognition
Legal classification
Schedule I controlled substance in the United States
Reasons for legal classification
potential for abuse, lack of accepted medical use
Adverse effects
increased heart rate, elevated blood pressure, severe psychological distress.
Check Digit Verification of cas no
The CAS Registry Mumber 20731-70-8 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,0,7,3 and 1 respectively; the second part has 2 digits, 7 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 20731-70:
(7*2)+(6*0)+(5*7)+(4*3)+(3*1)+(2*7)+(1*0)=78
78 % 10 = 8
So 20731-70-8 is a valid CAS Registry Number.
20731-70-8Relevant articles and documents
Novel tetrahydro-β-carboline-1-carboxylic acids as inhibitors of mitogen activated protein kinase-activated protein kinase 2 (MK-2)
Trujillo, John I.,Meyers, Marvin J.,Anderson, David R.,Hegde, Shridhar,Mahoney, Matthew W.,Vernier, William F.,Buchler, Ingrid P.,Wu, Kun K.,Yang, Syaluan,Hartmann, Susan J.,Reitz, David B.
, p. 4657 - 4663 (2008/02/13)
A structure-activity relationship study was conducted on a series of tetrahydro-β-carboline-1-carboxylic acid analogs in order to identify the key functionality responsible for activity against the mitogen-activated protein kinase-activated protein kinase 2 enzyme (MK-2). The compounds were further evaluated for their ability to inhibit TNFα production in U937 cells and in vivo. These compounds represent a novel structural class of compounds capable of inhibiting MK-2 with remarkable selectivity.
