20736-08-7

Basic information

• Product Name: Saikosaponin C
• Synonyms: SAIKOSAPONIN C;Saikosaponian C;SAIKOSAPONIN C(P);(3beta,4alpha,16beta)-13,28-Epoxy-16,23-dihydroxyolean-11-en-3-yl O-6-deoxy-alpha-L-mannopyranosyl-(1-4)-O-beta-D-glucopyranosyl-(1-6)-beta-D-glucopyranoside;[13,28-Epoxy-16β-hydroxyolean-11-en-3β-yl]4-O-(6-deoxy-α-L-mannopyranosyl)-6-O-(β-D-glucopyranosyl)-β-D-glucopyranoside;beta-D-Glucopyranoside, (3beta,4alpha,16beta)-13,28-epoxy-16,23-dihydroxyolean-11-en-3-yl-O-6-deoxy-alpha-L-mannopyranosyl-(1->4)-O-[beta-D-glucopyranosyl-(1->6)]-);Saikosaponin c standard;SAIKOSAPONIN A(P)
• CAS NO: 20736-08-7
• Molecular Formula: C48H78O18
• Molecular Weight: 943.12
• Product Categories: Saponins;chemical reagent;pharmaceutical intermediate;phytochemical;reference standards from Chinese medicinal herbs (TCM).;standardized herbal extract
• Mol File: 20736-08-7.mol
• Article Data: 0

Chemical Properties

• Melting Point: 310-314 °C(Solv: methanol (67-56-1))
• Appearance: /
• Density: 1.405 g/cm³
• Refractive Index: 1.623
• Storage Temp.: Refrigerator, under inert atmosphere
• Solubility: Methanol (Slightly), Pyridine (Slightly)
• PKA: 12.76±0.70(Predicted)
• CAS DataBase Reference: Saikosaponin C(CAS DataBase Reference)
• NIST Chemistry Reference: Saikosaponin C(20736-08-7)
• EPA Substance Registry System: Saikosaponin C(20736-08-7)

Safety Data

• Hazardous Substances Data: 20736-08-7(Hazardous Substances Data)

Usage

Description

Saikosaponin C is a natural compound derived from the Bupleurum genus of plants, which are traditionally used in Chinese medicine. It is known for its various pharmacological properties, including anti-inflammatory, anti-apoptotic, and neuroprotective effects.

Uses

Used in Pharmaceutical Industry:
Saikosaponin C is used as an inhibitor of liposaccharide-induced apoptosis through the suppression of caspase-3 activation. This makes it a potential candidate for the development of neuroprotective agents, which can be beneficial in treating conditions associated with neuronal damage and cell death, such as neurodegenerative diseases and brain injuries.
Used in Neuroprotective Applications:
Saikosaponin C is used as a neuroprotective agent for its ability to protect neurons from damage and cell death. This application is particularly relevant in the context of neurodegenerative diseases, where neuronal loss is a significant contributing factor to the progression of the disease. By inhibiting apoptosis and promoting neuronal survival, Saikosaponin C may offer therapeutic potential in the treatment and management of such conditions.

InChI:InChI=1/C48H78O17/c1-22-30(51)32(53)36(57)40(61-22)65-38-24(20-59-39-35(56)33(54)31(52)23(19-49)62-39)63-41(37(58)34(38)55)64-29-11-12-44(6)25(43(29,4)5)9-13-45(7)26(44)10-14-48-27-17-42(2,3)15-16-47(27,21-60-48)28(50)18-46(45,48)8/h10,14,22-41,49-58H,9,11-13,15-21H2,1-8H3/t22-,23+,24+,25-,26+,27+,28-,29-,30-,31+,32+,33-,34+,35+,36+,37+,38+,39+,40-,41-,44-,45+,46-,47+,48-/m0/s1