20743-91-3

Basic information

• Product Name: Benzene, 1-(hexyloxy)-4-methoxy-
• CAS NO: 20743-91-3
• Molecular Formula: C13H20O2
• Molecular Weight: 208.301
• Mol File: 20743-91-3.mol
• Article Data: 10

Chemical Properties

• CAS DataBase Reference: Benzene, 1-(hexyloxy)-4-methoxy-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzene, 1-(hexyloxy)-4-methoxy-(20743-91-3)
• EPA Substance Registry System: Benzene, 1-(hexyloxy)-4-methoxy-(20743-91-3)

Safety Data

• Hazardous Substances Data: 20743-91-3(Hazardous Substances Data)

Upstream product

• 104-92-7 1-bromo-4-methoxy-benzene 
• 111-27-3 hexan-1-ol 
• 122004-89-1 6-(4-methoxyphenoxy)hexan-1-ol 
• 150-76-5 4-methoxy-phenol 
• 4286-55-9 1-bromo-6-hexanol 
• 1383151-90-3 C₁₃H₁₈O₃ 
• 696-62-8 para-iodoanisole 
• 111-25-1 1-bromo-hexane 
• 92149-07-0 4,7-dimethoxy-1,10-phenanthroline 
• 544-10-5 1-Chlorohexane 

Downstream Products

• 218141-98-1 1,4-bis(chloromethyl)-2-hexyloxy-5-methoxybenzene 
• 1265919-63-8 1-hexyloxy-4-methoxy-2,5-dinitrobenzene 
• 1265919-64-9 1-hexyloxy-4-methoxy-3-nitrobenzene 

Relevant articles and documents

Copper-catalyzed hydroxylation of aryl halides: Efficient synthesis of phenols, alkyl aryl ethers and benzofuran derivatives in neat water

A thorough study of environmentally friendly hydroxylation of aryl halides is presented. The best protocol consists of hydroxylation of different aryl bromides and electron-deficient aryl chlorides by water solution of tetrabutylammonium hydroxide catalyzed by Cu2O/4,7-dihydroxy-1,10-phenanthroline. Various phenol derivatives can be obtained in excellent selectivity and great functional group tolerance. This methodology also provides a direct pathway for the formation of alkyl aryl ethers and benzofuran derivatives in a one-pot tandem reaction.

Unprecedented Regioregular Poly(1,4-arylene)s Prepared by Nickel(II)-Catalyzed Cross-Coupling Polymerization of 2,5-Disubstituted Bromo(chloro)arylene

The unprecedented synthesis of regioregular head-to-tail-type poly(1,4-arylene)s bearing different substituents at the 2- and 5-positions is described. They were prepared by the polymerization of 2,5-disubstituted bromo(chloro)arylenes by selective halogen–metal exchange with a Grignard reagent and subsequent cross-coupling polymerization with a nickel catalyst [NiCl2(dppp)]. Formation of the regioregular poly(1,4-arylene)s were confirmed by NMR spectroscopy, and showed remarkable differences to those polymers having uncontrolled regioregularity. Polymerization of bromo(chloro)arylenes with a chiral alkoxy substituent also led to the regioregular head-to-tail-type polyarylene, which demonstrated circular dichroism, thus suggesting formation of a structure with higher-order regularity.

Copper and l-sodium ascorbate catalyzed hydroxylation and aryloxylation of aryl halides

CuSO4·5H2O and NaAsc catalyzed hydroxylation and C-O/C-S cross-coupling reactions of aryl halides with phenols or 4-methylbenzenethiol were described. A wide range of substrates and test cases highlight the synthetic utility of the approach. A series of phenols, diaryl ethers, alkylaryl ethers, and diaryl thioethers were synthesized in high yield.