207449-47-6

Basic information

• Product Name: (S)-3-(4-Cyano-phenyl)-2-(2-trimethylsilanyl-ethoxycarbonylamino)-propionic acid methyl ester
• Synonyms: (S)-3-(4-Cyano-phenyl)-2-(2-trimethylsilanyl-ethoxycarbonylamino)-propionic acid methyl ester
• CAS NO: 207449-47-6
• Molecular Weight: 348.474
• Mol File: 207449-47-6.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (S)-3-(4-Cyano-phenyl)-2-(2-trimethylsilanyl-ethoxycarbonylamino)-propionic acid methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: (S)-3-(4-Cyano-phenyl)-2-(2-trimethylsilanyl-ethoxycarbonylamino)-propionic acid methyl ester(207449-47-6)
• EPA Substance Registry System: (S)-3-(4-Cyano-phenyl)-2-(2-trimethylsilanyl-ethoxycarbonylamino)-propionic acid methyl ester(207449-47-6)

Safety Data

• Hazardous Substances Data: 207449-47-6(Hazardous Substances Data)

Upstream product

• 298693-79-5 methyl (S)-2-((tert-butoxycarbonyl)amino)-3-(4-cyanophenyl)propanoate 
• 131724-45-3 (S)-2-((tert-butoxycarbonyl)amino)-3-(4-cyanophenyl)propanoic acid 
• 2916-68-9 2-(Trimethylsilyl)ethanol 
• 80149-80-0 2-(Trimethylsilyl)ethyl 4-nitrophenyl carbonate 
• 272784-76-6 (S)-methyl 2-amino-3-(4-cyanophenyl)propanoate 

Downstream Products

• 207449-48-7 (S)-3-(4-Aminomethyl-phenyl)-2-(2-trimethylsilanyl-ethoxycarbonylamino)-propionic acid methyl ester 

Relevant articles and documents

Solid phase synthesis of benzylamine-derived sulfonamide library

Using solid phase synthesis, a library has been constructed of benzylamine-derived sulfonamides which have strong inhibitory activity against the blood coagulant thrombin. The library compounds were obtained in good yield and high purity; four of these thrombin inhibitors showed nanomolar potency (Ki 600-10 nM).