20763-30-8

Basic information

• Product Name: 2-amino-2-(cyclohexadien-1,4-yl)acetic acid
• Synonyms: 2-amino-2-(cyclohexadien-1,4-yl)acetic acid;(2R)-Amino(cyclohexa-1,4-dien-1-yl) acetic acid;Dl-Dihydrophenylglycine;-Amino1,4-cyclohexadiene-1-acetic acid;DHG;DL-1,4-Cyclohexadiene-1-glycine;2-(1,4-Cyclohexadienyl)-glycine;2-Amino-2-(1,4-cyclohexadien-1-yl)acetic acid
• CAS NO: 20763-30-8
• Molecular Formula: C₈H₁₁NO₂
• Molecular Weight: 153.17844
• EINECS: 244-014-7
• Mol File: 20763-30-8.mol
• Article Data: 2

Chemical Properties

• Melting Point: 297 °C (decomp)
• Boiling Point: 279.4°Cat760mmHg
• Flash Point: 122.8°C
• Appearance: /
• Density: 1.226g/cm³
• Vapor Pressure: 0.00107mmHg at 25°C
• Refractive Index: 1.573
• PKA: 2.17±0.10(Predicted)
• CAS DataBase Reference: 2-amino-2-(cyclohexadien-1,4-yl)acetic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 2-amino-2-(cyclohexadien-1,4-yl)acetic acid(20763-30-8)
• EPA Substance Registry System: 2-amino-2-(cyclohexadien-1,4-yl)acetic acid(20763-30-8)

Safety Data

• Hazardous Substances Data: 20763-30-8(Hazardous Substances Data)

Usage

Synthesis Reference(s)

Tetrahedron Letters, 28, p. 1173, 1987 DOI: 10.1016/S0040-4039(00)95318-8

InChI:InChI=1/C8H11NO2/c9-7(8(10)11)6-4-2-1-3-5-6/h1-2,5,7H,3-4,9H2,(H,10,11)

Upstream product

• 2835-06-5 phenylglycin 
• 26774-88-9 (R)?2?(2,5?dihydrophenyl)glycine 

Downstream Products

• 35264-05-2 2-((tert-butoxycarbonyl)amino)-2-cyclohexylacetic acid 
• 93939-80-1 D-α-(1-methoxy-croton-3-ylamino)-α-1,4-cyclohexadienyl-acetic acid sodium salt 
• 51013-53-7 D(-)-α-amino-α-(1,4-cyclohexadienyl) acetic acid chloride hydrochloride 
• 1059200-16-6 2-(2,5-dihydrophenyl)glycinol 

Relevant articles and documents

Synthesis of cephalosporin-type antibiotics by coupling of their β-lactam nucleus and racemic amino acid side chains using a clathration-induced asymmetric transformation

The cephalosporin-type antibiotics Cephalexin, Cephradine and Cefadroxil have been prepared by coupling of their β-lactam nucleus and racemic amino acid side chain precursors. The initially obtained mixture of cephalosporin epimers is subjected to a clathration-induced asymmetric transformation which results in the epimerization of the epi-cephalosporin into the cephalosporin with the correct diastereomeric configuration.