20771-12-4

Basic information

• Product Name: Methyl 6-O-acetyl-β-D-glucopyranoside
• Synonyms: β-D-Glucopyranoside, methyl, 6-acetate
• CAS NO: 20771-12-4
• Molecular Formula: C₉H₁₆O₇
• Molecular Weight: 236.21914
• Mol File: 20771-12-4.mol
• Article Data: 11

Chemical Properties

• Appearance: /
• CAS DataBase Reference: Methyl 6-O-acetyl-β-D-glucopyranoside(CAS DataBase Reference)
• NIST Chemistry Reference: Methyl 6-O-acetyl-β-D-glucopyranoside(20771-12-4)
• EPA Substance Registry System: Methyl 6-O-acetyl-β-D-glucopyranoside(20771-12-4)

Safety Data

• Hazardous Substances Data: 20771-12-4(Hazardous Substances Data)

Upstream product

• 4356-79-0 methyl 6-O-acetyl-2,3,4-tri-O-benzyl-β-D-glucopyranoside 
• 88037-29-0 methyl 4-O-acetyl-6-O-trityl-β-D-glucopyranoside 
• 79384-28-4 methyl 6-O-(2-carboxyacetyl)-β-D-glucopyranoside 
• 108-05-4 vinyl acetate 
• 709-50-2 methyl beta-D-glucopyranoside 
• 141-78-6 ethyl acetate 
• 4860-85-9 methyl 2,3,4,6-tetra-O-acetyl-β-D-glucopyranoside 
• 108-24-7 acetic anhydride 
• 75-36-5 acetyl chloride 
• 153874-61-4 methyl 6-O-<2-(methoxycarbonyl)acetyl>-β-D-glucopyranoside 
• 51842-38-7 methyl 2,3-di-O-benzyl-6-O-trityl-β-D-glucopyranoside 
• 51842-15-0 methyl 2,3-di-O-benzyl-4-O-acetyl-6-O-trityl-β-D-glucopyranoside 
• 6988-40-5 methyl 2,3-di-O-benzyl-β-D-glucopyranoside 
• 2466-76-4 N-Acetylimidazole 

Relevant articles and documents

Selective Acetylation of the Primary Hydroxyl Group in Methyl D-Hexopyranosides with a Mixture of Acetic Anhydride and Acetic Acid

Abstract—: 6-O-Acetylated derivatives of D-hexopyranosides are valuable intermediates in synthetic carbohydrate chemistry. We have developed a new simple procedure for selective acetylation of the primary hydroxyl group in methyl D-hexopyranosides consisting in treatment with a mixture of acetic anhydride and acetic acid at 50°C. As a result, corresponding 6-acetates were formed in 40–50% yield.

A basic germanodecatungstate with a - 7 charge: Efficient chemoselective acylation of primary alcohols

The synthesis of highly negatively charged polyoxometalates with electrically and structurally controlled uniform basic sites can lead to the unique base catalysis. In this work, a γ-Keggin germanodecatungstate, [γ-HGeW10O36]7- (A), having a -7 charge was, for the first time, successfully synthesized by the reaction of [γ-H2GeW10O36]6- with one equivalent of [(n-C4H9)4N]OH under non-aqueous conditions. The activities of germanodecatungstates for base-catalyzed reactions dramatically increased with increase in the number negative charges from -6 to -7. In the presence of A, various combinations of acylating agents and primary alcohols including those with acid-sensitive functional groups chemoselectively gave the desired acylated products in high yields even under the stoichiometric conditions.

Carbohydrate esterases of family 2 are 6-O-deacetylases

Three acetyl esterases (AcEs) from the saprophytic bacteria Cellvibrio japonicus and Clostridium thermocellum, members of the carbohydrate esterase (CE) family 2, were tested for their activity against a series of model substrates including partially acet