20780-72-7

Basic information

• Product Name: 4-BROMOISATIN
• Synonyms: 4-BROMO-1H-INDOLE-2,3-DIONE;4-BROMOINDOLE-2,3-DIONE;4-BROMOINDOLINE-2,3-DIONE;4-BROMOISATIN;BUTTPARK 50\07-93;4-Bromoisatin 98%;4-BROMO-2,3-INDOLINEDIONE 97.0%(MIN)(HPLC);4-Broisatin
• CAS NO: 20780-72-7
• Molecular Formula: C₈H₄BrNO₂
• Molecular Weight: 226.03
• EINECS: 1312995-182-4
• Product Categories: Halides;Indoline & Oxindole;Indoles;Simple Indoles;Fused Ring Systems
• Mol File: 20780-72-7.mol
• Article Data: 26

Chemical Properties

• Melting Point: 253-256
• Appearance: /
• Density: 1.826 g/cm³
• Refractive Index: 1.649
• Storage Temp.: Sealed in dry,Room Temperature
• Solubility: soluble in Dimethylformamide
• PKA: 8.73±0.20(Predicted)
• CAS DataBase Reference: 4-BROMOISATIN(CAS DataBase Reference)
• NIST Chemistry Reference: 4-BROMOISATIN(20780-72-7)
• EPA Substance Registry System: 4-BROMOISATIN(20780-72-7)

Safety Data

• Hazard Codes: Xi
• HazardClass: IRRITANT
• Hazardous Substances Data: 20780-72-7(Hazardous Substances Data)

Usage

General Description

4-Bromoisatin is a chemical compound with the molecular formula C8H5BrO2. It is a synthetic derivative of isatin, a naturally occurring compound found in plants and animal tissues. 4-Bromoisatin is used in the production of pharmaceuticals, agrochemicals, and as a reagent in chemical synthesis. It has been studied for its potential antitumor and anti-inflammatory properties, as well as its ability to inhibit the activity of certain enzymes. 4-BROMOISATIN has also been investigated for its potential use in organic light emitting diodes (OLEDs) and as a fluorescent probe in biological imaging applications.

InChI:InChI=1/C8H4BrNO2/c9-4-2-1-3-5-6(4)7(11)8(12)10-5/h1-3H,(H,10,11,12)

Upstream product

• 65971-74-6 (E)-N-(3-bromophenyl)-2-(hydroxyimino)acetamide 
• 195526-38-6 N,N'-bis-(3-bromo-phenyl)-thiourea 
• 65971-74-6 N-(3-bromophenyl)-2-(hydroxyimino)ethanamide 
• 591-19-5 m-Bromoaniline 
• 302-17-0 chloral hydrate 
• 1388071-44-0 C₈H₄Br₃NO 
• 86626-38-2 4-bromo-2,3-dihydro-1H-indole 
• 52488-36-5 4-bromo-1H-indole 

Downstream Products

• 20776-48-1 2-amino-6-chlorobenzoic acid 
• 188181-25-1 9-Bromo-3-oxo-2-phenyl-3,5-dihydro-2H-pyridazino[4,3-b]indole-4-carboxylic acid 
• 188181-07-9 9-Bromo-3-oxo-2-phenyl-3,5-dihydro-2H-pyridazino[4,3-b]indole-4-carboxylic acid ethyl ester 
• 77326-62-6 2-amino-6-bromobenzonitrile 
• 861609-00-9 2-bromo-6-(carboxymethyl-amino)-benzoic acid 
• 77603-45-3 5-bromo-2,4-dihydro-1H-3,1-benzoxazine-2,4-dione 
• 1019767-85-1 4-bromo-3-hydroxy-3-(3-hydroxy-6-methoxypyridin-2-yl)-1,3-dihydro-2H-indol-2-one 
• 1021048-54-3 4-bromo-1-(4-fluorobenzyl)indoline-2.3-dione 
• 884855-67-8 4-bromo-1-methylindoline-2,3-dione 
• 1146746-58-8 2'-amino-4-bromo-1'-(4-methoxyphenyl)-7',7'-dimethyl-2,5'-dioxo-5',6',7',8'-tetrahydro-1'H-spiro[indoline-3,4'-quinoline]-3'-carbonitrile 
• 1243153-53-8 C₁₅H₁₂BrNO₂ 
• 1219834-22-6 5-bromoquinoline-4-carboxylic acid 
• 1243238-19-8 (3R)-4-bromo-3-hydroxy-3-[(1S,2E)-1-phenylpent-2-enyl]indolin-2-one 
• 1020972-38-6 1-benzyl-4-bromoindoline-2,3-dione 

Relevant articles and documents

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The invention discloses a method for preparing indole-2,3-dione derivatives by catalytic oxidation of microwave copper/peroxyacetic acid. The method comprises the following steps: a catalytic amount of catalyst copper iodide, indole, a derivative of the indole and peroxyacetic acid are added into a reaction vessel, wherein the indole, the derivative of the indole and the peroxyacetic acid are usedas raw materials, ethanol is used as a solvent, the reaction vessel is placed into a microwave reaction instrument, a reaction is performed at certain temperature and power, after a certain time, reduced-pressure concentration is performed, and a product is purified by column chromatography. The method provided by the invention is a method having novel raw materials, simple operation and high efficiency used for preparing a benzimidazole derivative; and compared with the prior art, the method provided by the invention has an obviously-accelerated reaction speed than that under conventional heating, mild reaction conditions, simple operation, a high yield, safety, low costs and environmental protection.