20781-22-0

Basic information

• Product Name: 2,6-Dimethoxybenzylamine
• Synonyms: 2,6-DIMETHOXYBENZYLAMINE;RARECHEM AL BW 1093;(2,6-dimethoxyphenyl)methanamine;2,6-Dimethoxybenzylamine 95%;2,6-Dimethoxybenzyla;(2,6-Dimethoxyphenyl)methylamine
• CAS NO: 20781-22-0
• Molecular Formula: C₉H₁₃NO₂
• Molecular Weight: 167.21
• EINECS: -0
• Product Categories: Anilines, Aromatic Amines and Nitro Compounds;Amine
• Mol File: 20781-22-0.mol
• Article Data: 4

Chemical Properties

• Melting Point: 82 °C
• Boiling Point: 108-110°C 1mm
• Flash Point: 108-110°C/1mm
• Appearance: /
• Density: 1.062g/cm³
• Vapor Pressure: 0.0139mmHg at 25°C
• Refractive Index: 1.522
• PKA: 9.23±0.10(Predicted)
• Sensitive: Moisture Sensitive/Air Sensiti
• BRN: 2965661
• CAS DataBase Reference: 2,6-Dimethoxybenzylamine(CAS DataBase Reference)
• NIST Chemistry Reference: 2,6-Dimethoxybenzylamine(20781-22-0)
• EPA Substance Registry System: 2,6-Dimethoxybenzylamine(20781-22-0)

Safety Data

• Hazard Codes: C
• Statements: 34
• Safety Statements: 26-36/37/39-45
• RIDADR: 3259
• HazardClass: 8
• PackingGroup: III
• Hazardous Substances Data: 20781-22-0(Hazardous Substances Data)

Usage

Chemical Properties

white to light yellow crystal powde

InChI:InChI=1/C9H13NO2/c1-11-8-4-3-5-9(12-2)7(8)6-10/h3-5H,6,10H2,1-2H3

Upstream product

• 16932-49-3 2,6-dimethoxybenzonitrile 
• 3392-97-0 2,6-dimethoxybenzaldehyde 

Downstream Products

• 792917-54-5 2-(3-{(2R)-2-[(2R)-2-([tert-Butyl(dimethyl)silyl]oxy}-2-(4-hydroxy-3-hydroxymethyl-phenyl)-ethylamino]-propyl}-phenyl)-N-(2,6-dimethoxybenzyl)-acetamide 
• 222035-26-9 2-Oxo-3-[(4-sulfamoyl-phenyl)-hydrazono]-2,3-dihydro-1H-indol-5-carboxylic acid-2,6-dimethoxy-benzylamide 
• 1021300-44-6 3-(2,6-dimethoxybenzyl)-1,5,7-trimethyl-2,4-dioxo-3-azabicyclo[3.3.1]nonane-7-carboxylic acid 
• 1042423-57-3 C₂₀H₁₉NO₆ 
• 1144854-44-3 C₁₉H₂₃N₅O₃ 
• 927892-11-3 4-bromo-N-(2,6-dimethoxybenzyl)-2-nitrobenzamide 
• 927892-16-8 5-chloro-N-(2,6-dimethoxybenzyl)-2-nitrobenzamide 
• 927892-00-0 N-(2,6-dimethoxybenzyl)-2-nitrobenzamide 
• 927900-53-6 N-(2,6-dimethoxybenzyl)-N'-pyridin-2-yl-guanidine acetate 
• 927901-35-7 N-(6-bromopyridin-2-yl)-N'-(2,6-dimethoxybenzyl)guanidine 
• 927901-36-8 N-(4-bromopyridin-2-yl)-N'-(2,6-dimethoxybenzyl)guanidine 
• 927900-48-9 N-(2,6-dimethoxybenzyl)-N'-(5-iodopyridin-2-yl)guanidine 
• 1235889-58-3 C₁₆H₁₇NO₂ 

Relevant articles and documents

Palladium-catalyzed oxygenation of C(sp2)-H and C(sp3)-H bonds under the assistance of oxalyl amide

A practical palladium-catalyzed γ-oxygenation of C(sp2)-H and C(sp3)-H bonds under the assistance of oxalyl amide with PhI(OAc)2 as oxidant was developed. Selective alkoxylation or acetoxylation of oxalyl amide protected benzyl amine was achieved in high yield. The oxalyl amide protected α-substituted propylamines could be transformed into acetoxylated products in good to excellent yields.

2-substituted parazoleamino-4-substituted amino-5-pyrimidine formamide compound, composition and application thereof

The invention relates to a series of new compounds as a JAK inhibitor, as well as compositions and applications thereof, and particularly provides a series of compounds (I) that have a strong JAK inhibiting activity, or stereisomers, geometrical isomers, tautomers, pharmaceutically acceptable salts, prodrugs, metabolites, isotope derivatives, and solvates, as well as medicine compositions comprising such compounds. The invention also discloses applications of the compounds or the medicine compositions in preparation of a medicine, which is used for treatment of autoimmune diseases or cancer.