207986-25-2 Usage
Description
ALPHA-BROMO-4-(DIETHYLAMINO)ACETOPHENONE is a chemical compound that serves as a pharmaceutical intermediate and is also used as a primary and secondary intermediate in the synthesis of various pharmaceuticals.
Uses
Used in Pharmaceutical Industry:
ALPHA-BROMO-4-(DIETHYLAMINO)ACETOPHENONE is used as a pharmaceutical intermediate for the synthesis of various drugs and medications. Its unique chemical structure allows it to be a key component in the development of new pharmaceuticals with potential therapeutic benefits.
Used in Chemical Synthesis:
ALPHA-BROMO-4-(DIETHYLAMINO)ACETOPHENONE is used as a primary and secondary intermediate in the synthesis of other chemical compounds. Its versatile structure makes it a valuable building block for the creation of new molecules with potential applications in various industries, including pharmaceuticals, agrochemicals, and materials science.
Check Digit Verification of cas no
The CAS Registry Mumber 207986-25-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,0,7,9,8 and 6 respectively; the second part has 2 digits, 2 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 207986-25:
(8*2)+(7*0)+(6*7)+(5*9)+(4*8)+(3*6)+(2*2)+(1*5)=162
162 % 10 = 2
So 207986-25-2 is a valid CAS Registry Number.
InChI:InChI=1/C12H16BrNO/c1-3-14(4-2)11-7-5-10(6-8-11)12(15)9-13/h5-8H,3-4,9H2,1-2H3
207986-25-2Relevant articles and documents
Nucleus-independent chemical shift (NICS) as a criterion for the design of new antifungal benzofuranones
González-Chávez, Marco Martín,González-Chávez, Rodolfo,Méndez, Francisco,Martínez, Roberto,Ni?o-Moreno, Perla Del Carmen,Ojeda-Fuentes, Luis Enrique,Richaud, Arlette,Zerme?o-Macías, María de los ángeles
, (2021/08/30)
The assertion made by Wu et al. that aromaticity may have considerable implications for molecular design motivated us to use nucleus-independent chemical shifts (NICS) as an aromaticity criterion to evaluate the antifungal activity of two series of indol-4-ones. A linear regression analysis of NICS and antifungal activity showed that both tested variables were significantly related (p –1 for Candida glabrata, Candida krusei and Candida guilliermondii with compounds 15-32, 15-15 and 15-1. The MIC for filamentous fungi was 1.95 μg·mL–1 for Aspergillus niger for compounds 15-1, 15-33 and 15-34. The results obtained support the use of NICS in the molecular design of compounds with antifungal activity.
