20807-66-3

Basic information

• Product Name: 3-hydroxy-4-(2-methylphenoxy)butanenitrile
• Synonyms: 3-hydroxy-4-(2-methylphenoxy)butanenitrile
• CAS NO: 20807-66-3
• Molecular Weight: 191.23
• Mol File: 20807-66-3.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 3-hydroxy-4-(2-methylphenoxy)butanenitrile(CAS DataBase Reference)
• NIST Chemistry Reference: 3-hydroxy-4-(2-methylphenoxy)butanenitrile(20807-66-3)
• EPA Substance Registry System: 3-hydroxy-4-(2-methylphenoxy)butanenitrile(20807-66-3)

Safety Data

• Hazardous Substances Data: 20807-66-3(Hazardous Substances Data)

Upstream product

• 7677-24-9 trimethylsilyl cyanide 
• 2210-79-9 o-Cresyl glycidyl ether 
• 25772-91-2 1-chloro-3-(2-methylphenoxy)propan-2-ol 
• 151-50-8 potassium cyanide 
• 143-33-9 sodium cyanide 

Downstream Products

• 20807-69-6 4-(o-Tolyloxy)-3-hydroxy-buttersaeure 
• 20807-68-5 4-(o-Tolyloxy)-3-hydroxy-buttersaeureamid 
• 20807-67-4 4-(o-Tolyloxy)-3-hydroxy-buttersaeureaethylester 

Relevant articles and documents

A facile preparation of (±)-β-hydroxy nitriles and their enzymatic resolution with lipases

A simple and efficient method for the preparation of racemic 4-aryloxy-3-hydroxybutanenitriles is described. Lipase mediated kinetic resolution in organic media was then utilised to effect enantioseparation. Lipases from different sources were screened in the resolution reaction using a number of organic solvents. Enantiomeric excesses of up to 99% were obtained by employing lipase from Pseudomonas cepacia in di-iso-propyl ether medium.