20808-85-9Relevant articles and documents
A Novel Addition-Rearrangement of O-(1-Benzotriazolylaklyl)oximes with Organolithium Reagents. Convenient Non-oxidative Conversions of Aldehydes into Amides
Katritzky, Alan R.,Jiang, Jinlong,Greenhill, John V.,Steel, Peter J.
, p. 3055 - 3060 (2007/10/02)
Condensation of an aldehyde, an oxime and benzotriazole gives an O-(1-benzotriazolylalkyl)oxime which undergoes an addition-rearrangement on treatment with an organolithium reagent.This reaction provides a novel non-oxidative method for the transformation of aldehydes into amides which has afforded several new N-monosubstituted amides with crowded structures.Grignard reactions of the O-(1-benzotriazolylalkyl)oximes give alcohols as the major products.