208111-36-8

Basic information

• Product Name: N-(3-Chloro-4-fluorobenzoyl)-4-fluoro-4-N-(3-Chloro-4-fluorobenzoyl)-4-fluoro-4-hydroxymethylpiperidine
• Synonyms: N-(3-Chloro-4-fluorobenzoyl)-4-fluoro-4-N-(3-Chloro-4-fluorobenzoyl)-4-fluoro-4-hydroxymethylpiperidine;(3-Chloro-4-fluorophenyl)[4-fluoro-4-(hydroxymethyl)-1-piperidinyl]methanone
• CAS NO: 208111-36-8
• Molecular Formula: C₁₃H₁₄ClF₂NO₂
• Molecular Weight: 289.7055664
• Product Categories: Pyridine series
• Mol File: 208111-36-8.mol
• Article Data: 2

Chemical Properties

• Melting Point: 188-190℃
• Boiling Point: 442.537 °C at 760 mmHg
• Flash Point: 221.439 °C
• Appearance: /
• Density: 1.38
• PKA: 14.94±0.10(Predicted)
• CAS DataBase Reference: N-(3-Chloro-4-fluorobenzoyl)-4-fluoro-4-N-(3-Chloro-4-fluorobenzoyl)-4-fluoro-4-hydroxymethylpiperidine(CAS DataBase Reference)
• NIST Chemistry Reference: N-(3-Chloro-4-fluorobenzoyl)-4-fluoro-4-N-(3-Chloro-4-fluorobenzoyl)-4-fluoro-4-hydroxymethylpiperidine(208111-36-8)
• EPA Substance Registry System: N-(3-Chloro-4-fluorobenzoyl)-4-fluoro-4-N-(3-Chloro-4-fluorobenzoyl)-4-fluoro-4-hydroxymethylpiperidine(208111-36-8)

Safety Data

• Hazardous Substances Data: 208111-36-8(Hazardous Substances Data)

Usage

Description

N-(3-Chloro-4-fluorobenzoyl)-4-fluoro-4-N-(3-Chloro-4-fluorobenzoyl)-4-fluoro-4-hydroxymethylpiperidine is a complex chemical compound characterized by a piperidine ring with multiple functional groups. It features 4-fluoro-4-hydroxymethyl and 3-chloro-4-fluorobenzoyl substitutions, which may contribute to its potential pharmacological properties. The presence of the piperidine ring, commonly found in pharmaceuticals, suggests that this compound could be a promising candidate for drug development or other industrial applications.

Uses

Used in Pharmaceutical Industry:
N-(3-Chloro-4-fluorobenzoyl)-4-fluoro-4-N-(3-Chloro-4-fluorobenzoyl)-4-fluoro-4-hydroxymethylpiperidine is used as a potential pharmaceutical agent due to its complex structure and the presence of the piperidine ring, which is often associated with medicinal properties. Its specific functional groups may provide unique therapeutic effects, making it a candidate for further research and development in the pharmaceutical field.
Used in Chemical Research:
N-(3-Chloro-4-fluorobenzoyl)-4-fluoro-4-N-(3-Chloro-4-fluorobenzoyl)-4-fluoro-4-hydroxymethylpiperidine is also used in chemical research as a model for studying the effects of different functional groups on the properties and reactivity of organic molecules. Its structural complexity and potential biological activity make it an interesting subject for exploration in academic and industrial research settings.

Upstream product

• 208111-51-7 N-(3-chloro-4-fluorobenzoyl)-1-oxa-6-azaspiro<2,5>octane 
• 177-11-7 4,4-ethylenedioxy-piperidine 
• 65055-17-6 3-chloro-4-fluorobenzoyl chloride 
• 223632-64-2 1-[(3-chloro-4-fluorophenyl)carbonyl]piperidin-4-one 

Downstream Products

• 208111-37-9 N-(3-chloro-4-fluorobenzoyl)-4-fluoro-4-(4-methylphenylsulonuloxymethyl)-piperidine 
• 208111-39-1 N-(3-chloro-4-fluorobenzoyl)-4-fluoro-4-aminomethylpiperidine 
• 208110-64-9 (3-chloro-4-fluoro-phenyl)-(4-fluoro-4-{[(5-methyl-pyridin-2-ylmethyl)-amino]-methyl}-piperidin-1-yl)-methanone 
• 208111-38-0 N-(3-chloro-4-fluorobenzoyl)-4-fluoro-4-phthalimidomethylpiperidine 
• 208109-38-0 F 14679 

Relevant articles and documents

Pyridin-2-yl-methylamine derivatives, method of preparing and application as medicine

PCT No. PCT/FR97/02097 Sec. 371 Date May 21, 1999 Sec. 102(e) Date May 21, 1999 PCT Filed Nov. 20, 1997 PCT Pub. No. WO98/22459 PCT Pub. Date May 28, 1998The invention concerns novel pyridin-2-yl-methylamine derivatives of formula (I): in which: u represents hydrogen or methyl; v represents hydrogen, chlorine, or methyl; w represents hydrogen, fluorine, or methyl; x represents hydrogen or fluorine; y represents chlorine or methyl; z represents hydrogen, fluorine, chlorine, or methyl; A represents hydrogen, fluorine, chlorine, C1-C5 alkyl, fluoroalkyl, cyclopropyl, a 5-membered aromatic heterocyclic group, alkoxy or alkythio, amino, cyclic amino, or alkoxycarbonyl. These compounds are useful as medicines, in particular as antidepressants or analgesics.