2084868-04-0 Usage
Description
8,8'-disulfanediylbis(N-(2-(thiazol-2-yl)ethyl)quinoline-3-carboxamide) is a complex organic compound with a unique chemical structure that features a disulfide bond connecting two quinoline-3-carboxamide moieties, each with a thiazol-2-ylethyl group attached. 8,8'-disulfanediylbis(N-(2-(thiazol-2-yl)ethyl)quinoline-3-carboxamide) has been identified for its potential applications in various fields, particularly as an inhibitor of the proteasome subunit Rpn11.
Uses
Used in Pharmaceutical Industry:
8,8'-disulfanediylbis(N-(2-(thiazol-2-yl)ethyl)quinoline-3-carboxamide) is used as a novel inhibitor of the proteasome subunit Rpn11 for its potential role in the development of therapeutic strategies against various diseases, particularly those involving the ubiquitin-proteasome system.
The compound's ability to inhibit the proteasome subunit Rpn11 suggests that it may have applications in the treatment of cancer, as the ubiquitin-proteasome system plays a crucial role in regulating cellular processes such as protein homeostasis, cell cycle progression, and apoptosis. By targeting this specific subunit, the compound may help disrupt the balance of protein degradation and synthesis, leading to the accumulation of misfolded or damaged proteins and ultimately inducing cell death in cancer cells.
Additionally, the compound's unique chemical structure and its interaction with the proteasome subunit Rpn11 may also make it a valuable tool for researchers studying the ubiquitin-proteasome system and its role in various cellular processes. This could lead to a better understanding of the system's involvement in disease development and progression, as well as the identification of new therapeutic targets for the treatment of various diseases.
Check Digit Verification of cas no
The CAS Registry Mumber 2084868-04-0 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 2,0,8,4,8,6 and 8 respectively; the second part has 2 digits, 0 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 2084868-04:
(9*2)+(8*0)+(7*8)+(6*4)+(5*8)+(4*6)+(3*8)+(2*0)+(1*4)=190
190 % 10 = 0
So 2084868-04-0 is a valid CAS Registry Number.
2084868-04-0Relevant articles and documents
INHIBITORS OF RPN11
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Paragraph 00121; 00125; 00131, (2017/03/14)
Candidate compounds for specific inhibition of Rpn11 are represented by Formula 1a where each of R2, R3, R4, R5, R6, and R7 is independently selected from hydrogen (H), substituted and unsubstituted alkyl groups, carboxyl groups, or substituted and unsubstituted carboxyamides.
