208762-35-0

Basic information

• Product Name: (1R,3S)-3-[2-AMino-6-(cyclopropylaMino)-9H-purin-9-yl]cyclopentaneMethanol
• Synonyms: (1R,3S)-3-[2-AMino-6-(cyclopropylaMino)-9H-purin-9-yl]cyclopentaneMethanol
• CAS NO: 208762-35-0
• Molecular Formula: C14H20N6O
• Molecular Weight: 288.3482
• Product Categories: Impurities, Inhibitors, Nucleotides, Bases & Related Reagents, Pharmaceuticals, Intermediates & Fine Chemicals
• Mol File: 208762-35-0.mol
• Article Data: 0

Chemical Properties

• Boiling Point: 624.3±65.0 °C(Predicted)
• Appearance: /
• Density: 1.71±0.1 g/cm3(Predicted)
• Storage Temp.: -20°C Freezer
• Solubility: Methanol (Slightly), Water (Slightly)
• PKA: 15.05±0.10(Predicted)
• CAS DataBase Reference: (1R,3S)-3-[2-AMino-6-(cyclopropylaMino)-9H-purin-9-yl]cyclopentaneMethanol(CAS DataBase Reference)
• NIST Chemistry Reference: (1R,3S)-3-[2-AMino-6-(cyclopropylaMino)-9H-purin-9-yl]cyclopentaneMethanol(208762-35-0)
• EPA Substance Registry System: (1R,3S)-3-[2-AMino-6-(cyclopropylaMino)-9H-purin-9-yl]cyclopentaneMethanol(208762-35-0)

Safety Data

• Hazardous Substances Data: 208762-35-0(Hazardous Substances Data)

Usage

Description

Abacavir sulfate impurity E [WHO-IP] is a chemical compound that is identified as an impurity in Abacavir (A105000), a nucleoside reverse transcriptase inhibitor. It is characterized by its specific molecular structure, which is (1R,3S)-3-[2-Amino-6-(cyclopropylamino)-9H-purin-9-yl]cyclopentanemethanol.

Uses

Used in Pharmaceutical Industry:
Abacavir sulfate impurity E [WHO-IP] is used as a reference material for the identification and quantification of impurities in the manufacturing process of Abacavir. This is important for ensuring the quality, safety, and efficacy of the final drug product, as well as meeting regulatory requirements for pharmaceutical manufacturing.
Additionally, understanding the properties and effects of this impurity can contribute to the development of improved drug formulations and potential therapeutic applications related to Abacavir's primary use as an antiretroviral medication for the treatment of HIV-1 infection.