20894-63-7 Usage
Description
1-(2-NAPHTHYL)-3-(2-THIENYL)-2-PROPEN-1-ONE, a chemical compound belonging to the class of alpha, beta-unsaturated ketones, is a yellow crystalline solid with the molecular formula C17H12OS. It is known for its unique chemical properties that make it valuable in the synthesis of various organic compounds and pharmaceuticals.
Uses
Used in Pharmaceutical Synthesis:
1-(2-NAPHTHYL)-3-(2-THIENYL)-2-PROPEN-1-ONE is used as a key intermediate in the synthesis of pharmaceuticals for its unique chemical properties, contributing to the development of new drugs with potential therapeutic applications.
Used in Agrochemical Development:
In the agrochemical industry, 1-(2-NAPHTHYL)-3-(2-THIENYL)-2-PROPEN-1-ONE is used as a chemical building block for the creation of new agrochemicals, potentially enhancing crop protection and yield.
Used in Material Science:
1-(2-NAPHTHYL)-3-(2-THIENYL)-2-PROPEN-1-ONE is utilized as a component in the development of novel materials, leveraging its chemical properties to improve material performance and create innovative applications.
Used in Anti-Inflammatory Applications:
1-(2-NAPHTHYL)-3-(2-THIENYL)-2-PROPEN-1-ONE has been studied for its potential as an anti-inflammatory agent, with further research being conducted to understand its effects and potential uses in treating inflammation-related conditions.
Used in Anticancer Applications:
1-(2-NAPHTHYL)-3-(2-THIENYL)-2-PROPEN-1-ONE is also being investigated for its potential as an anticancer agent, with research focusing on its ability to target and affect cancer cells, possibly leading to the development of new cancer treatments.
Further research is ongoing to explore the full range of potential uses and effects of 1-(2-NAPHTHYL)-3-(2-THIENYL)-2-PROPEN-1-ONE in various fields, including pharmaceuticals, agrochemicals, and material science.
Check Digit Verification of cas no
The CAS Registry Mumber 20894-63-7 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,0,8,9 and 4 respectively; the second part has 2 digits, 6 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 20894-63:
(7*2)+(6*0)+(5*8)+(4*9)+(3*4)+(2*6)+(1*3)=117
117 % 10 = 7
So 20894-63-7 is a valid CAS Registry Number.
InChI:InChI=1/C17H12OS/c18-17(10-9-16-6-3-11-19-16)15-8-7-13-4-1-2-5-14(13)12-15/h1-12H/b10-9+
20894-63-7Relevant articles and documents
Naphthylchalcones induce apoptosis and caspase activation in a leukemia cell line: The relationship between mitochondrial damage, oxidative stress, and cell death
Winter, Evelyn,Chiaradia, Louise Domeneghini,De Cordova, Clarissa A.S.,Nunes, Ricardo José,Yunes, Rosendo Augusto,Creczynski-Pasa, Tania Beatriz
experimental part, p. 8026 - 8034 (2011/02/22)
In this study, we investigated the effects of 24 chalcone derivatives from 2-naphthylacetophenone toward a lymphoblastic leukemia cell line (L1210). Three compounds, called R7, R13, and R15, presented concentration- and time-dependent cytotoxicity and induced cellular death by apoptosis via mitochondrial injury and oxidative stress. The effects of these compounds appear to occur through different mechanisms because R13 and R7 induced a greater disturbance of mitochondrial potential, and all compounds induced disturbances of cellular ATP content and increased caspase-3 activity before cellular death. These compounds also interfered with antioxidant enzymes activities and GSH content through different mechanisms.
