2093393-05-4 Usage
Description
3-(3-(3-hydroxyphenyl)prop-2-yn-1-yl)-1,7-dimethyl-8-(methylsulfonyl)-3,7-dihydro-1H-purine-2,6-dione, also known as TC13172, is a highly potent Mixed Lineage Kinase Domain-Like protein (MLKL) inhibitor. It is a complex organic compound with a unique molecular structure that plays a significant role in various applications due to its ability to inhibit MLKL.
Uses
Used in Pharmaceutical Applications:
TC13172 is used as a potent MLKL inhibitor for the development of therapeutic strategies targeting various diseases and conditions. Its ability to inhibit MLKL makes it a promising candidate for the treatment of conditions where MLKL plays a crucial role in the pathology.
Used in Research and Development:
In the field of research, TC13172 is utilized as a valuable tool for studying the role of MLKL in cellular processes and disease mechanisms. Its potent inhibition of MLKL allows researchers to better understand the underlying pathways and develop targeted therapies.
Used in Drug Discovery:
TC13172 serves as a lead compound in the drug discovery process, where its structure and activity can be further optimized to improve potency, selectivity, and pharmacokinetic properties. This can lead to the development of more effective drugs targeting MLKL-related diseases.
Used in Anticancer Applications:
Although not explicitly mentioned in the provided materials, given its role as an MLKL inhibitor, TC13172 could potentially be investigated for its anticancer properties. MLKL has been implicated in cell death pathways, and its inhibition may offer therapeutic benefits in cancer treatment by modulating cell death mechanisms.
Used in Application Industry:
TC13172 is used as a [application type] for [application reason] in the [Application Industry]. For example, it could be used as a therapeutic agent for the treatment of specific diseases in the pharmaceutical industry or as a research tool in the biotechnology and academic research sectors.
Check Digit Verification of cas no
The CAS Registry Mumber 2093393-05-4 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 2,0,9,3,3,9 and 3 respectively; the second part has 2 digits, 0 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 2093393-05:
(9*2)+(8*0)+(7*9)+(6*3)+(5*3)+(4*9)+(3*3)+(2*0)+(1*5)=164
164 % 10 = 4
So 2093393-05-4 is a valid CAS Registry Number.
2093393-05-4Relevant articles and documents
MLKL INHIBITORS
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, (2018/09/26)
Purine derivatives that inhibit cellular necroptosis and/or human MLKL, pharmaceutical compositions thereof, and methods of treating an MLKL-mediated disorder with an effective amount of the compound or composition. Said MLKL-mediated disorder is pathology associated necroptosis, including ischemia-reperfusion damage, neurodegeneration, and inflammatory diseases such as acute pancreatitis, multiple sclerosis, inflammatory bowel disease, and allergic colitis.
