20938-94-7

Basic information

• Product Name: (+/-)-2-(4-methoxyphenyl)-2-hydroxy-N-isopropylethylamine
• CAS NO: 20938-94-7
• Molecular Weight: 209.288
• Mol File: 20938-94-7.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (+/-)-2-(4-methoxyphenyl)-2-hydroxy-N-isopropylethylamine(CAS DataBase Reference)
• NIST Chemistry Reference: (+/-)-2-(4-methoxyphenyl)-2-hydroxy-N-isopropylethylamine(20938-94-7)
• EPA Substance Registry System: (+/-)-2-(4-methoxyphenyl)-2-hydroxy-N-isopropylethylamine(20938-94-7)

Safety Data

• Hazardous Substances Data: 20938-94-7(Hazardous Substances Data)

Upstream product

• 6388-72-3 2-(4-methoxyphenyl)oxirane 
• 75-31-0 isopropylamine 
• 2632-13-5 2-Bromo-4'-methoxyacetophenone 
• 136068-29-6 (+)-2-(4-methoxyphenyl)-2-hydroxy-N-isopropylethylamine hydrochloride 

Relevant articles and documents

The acid-catalysed racemisation mechanism of catecholamines

The racemisation rates of (-)-adrenaline (1), ()-isoprenaline (2), (-)-2-(3,4-dimethoxyphenyl)-2-hydroxy-N-isopropylamine (3), (+)-2-(4-meethoxyphenyl)-2-hydroxy-N-isopropylethylamine (4), (+)-2-phenyl-2-hydroxy-N-isopropylehylamine (5), ()-phenylephrine(6), and (+)-1-phenylethanol(7) were compared. The racemisatton rates decreased in the following order: 7> 1 ≈ 2 > 3 ≈ 4 ? 5, 6. In general, the reactivity of the series of the phenylethanolamine compounds (1) - (6) was seen to increase sharply as the electron-releasing ability of the p-substituent of the aromatic nucleus increases. The results strengthen the notion that the acid-catalysed racemisation of catecholamines proceeds via a quinonoid-type intermediate.