209589-51-5Relevant articles and documents
A straightforward preparation of chiral 5-(aminomethyl)oxazole derivatives from α-amino esters and α-lithiated isocyanides
Ohba, Masashi,Kubo, Hiroyuki,Seto, Shigeki,Fujii, Tozo,Ishibashi, Hiroyuki
, p. 860 - 862 (1998)
An efficient and general preparation of several chiral N-protected 5- (aminomethyl)oxazoles has been accomplished by treatment of N-protected α- amino esters with α-lithiated isocyanides, obtained by metalation of methyl and benzyl isocyanides with BuLi or of ethyl isocyanide with lithium diisopropylamide.