209672-07-1Relevant articles and documents
Metal-Free Synthesis of Highly Substituted Pyridines by Formal [2+2+2] Cycloaddition under Mild Conditions
Xie, Lan-Gui,Shaaban, Saad,Chen, Xiangyu,Maulide, Nuno
supporting information, p. 12864 - 12867 (2016/10/04)
The synthesis of pyridines through direct intermolecular cycloaddition of alkynes and nitriles is a contemporary challenge in organic synthesis. A Br?nsted acid mediated formal [2+2+2] cycloaddition of heteroalkynes and nitriles was developed that proceed