209967-17-9

Basic information

• Product Name: 4-(2-aminophenyl)-1-butanol
• Synonyms: 4-(2-aminophenyl)-1-butanol
• CAS NO: 209967-17-9
• Molecular Weight: 165.235
• Mol File: 209967-17-9.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: 4-(2-aminophenyl)-1-butanol(CAS DataBase Reference)
• NIST Chemistry Reference: 4-(2-aminophenyl)-1-butanol(209967-17-9)
• EPA Substance Registry System: 4-(2-aminophenyl)-1-butanol(209967-17-9)

Safety Data

• Hazardous Substances Data: 209967-17-9(Hazardous Substances Data)

Upstream product

• 52103-12-5 3-iodopropyl tetrahydro-2H-pyran-2-yl ether 
• 74965-31-4 N-(tert-butoxycarbonyl)-o-toluidine 
• 4424-80-0 2,3,4,5-tetrahydro-1H-1-benzo[b]azepin-2-one 
• 1221498-35-6 4-(2-nitrophenyl)-butyraldehyde 
• 609-73-4 o-nitroiodobenzene 
• 209967-16-8 4-(o-nitrophenyl)-3-butyne-1-ol 
• 74117-98-9 4-(2-amino-phenyl)-butyric acid ethyl ester 

Downstream Products

• 1093413-28-5 4-(o-iodophenyl)butan-1-ol 
• 881417-15-8 1-(p-toluenesulfonyl)-2,3,4,5-tetrahydro-1H-1-benzazepin-2-one 
• 20426-63-5 1-(p-Tolylsulfonyl)-2,3,4,5-tetrahydro-1H-1-benzazepine 
• 953395-39-6 4-(2-(4-methylphenylsulfonamido)phenyl)butyl 2-ethynylbenzoate 
• 953395-38-5 4-(2-(4-methylphenylsulfonamido)phenyl)butyl 4-pentynoate 
• 953395-35-2 N-[2-(4-hydroxy-butyl)-phenyl]-4-methyl-benzenesulfonamide 
• 1701-57-1 2,3,4,5-tetrahydro-1Hbenzo[b]azepine 

Relevant articles and documents

Formal Deoxygenative Hydrogenation of Lactams Using PNHP-Pincer Ruthenium Complexes under Nonacidic Conditions

A formal deoxygenative hydrogenation of amides to amines with RuCl2(NHC)(PNHP) (NHC = 1,3-dimethylimizadol-2-ylidene, PNHP = bis(2-diphenylphosphinoethyl)amine) is described. Various secondary amides, especially NH-lactams, are reduced with H2 (3.0-5.0 MPa) to amines at a temperature range of 120-150 °C with 1.0-2.0 mol % of PNHP-Ru catalysts in the presence of Cs2CO3. This process consists of (1) deaminative hydrogenation of secondary amides to generate primary amines and alcohols, (2) dehydrogenative coupling of the transient amines with alcohols to generate imines, and (3) hydrogenation of imines to give the formally deoxygenated secondary amine products.

A mild inter- and intramolecular amination of aryl halides with a combination of CuI and CsOAc

A unique combination of CuI and CsOAc was found to catalyze aryl amination under mild conditions. The reaction takes place at room temperature or at 90 °C with broad functional group compatibility. The intramolecular reaction was able to form five-, six-, and seven-membered rings with various protecting groups on the nitrogen atom. The scope of the intermolecular amination, as well as its applications to unsymmetrical N,N′-dialkylated phenylenediamines, was investigated.