21010-60-6Relevant articles and documents
Oxidative Deaminations and Deisatinylations of Ugi-Azide and Ugi-3CR Products: A Two-Step MCR-Oxidation Protocol toward Functionalized α-Ketoamides and α-Ketotetrazoles
Foley, Christopher,Shaw, Arthur,Hulme, Christopher
, p. 2238 - 2241 (2017)
A new postcondensation multicomponent reaction (MCR) methodology, comprising oxidative deaminations enabling access to multiple privileged carbonyl-containing scaffolds in two steps, is described. These protocols allow facile access to functionalized α-ke
Copper(i) catalyzed oxidative hydrolysis of Ugi 3-component and Ugi-azide reaction products towards 2° α-ketoamides and α-ketotetrazoles
Collet, Jurri?n W.,Foley, Christopher,Shaw, Arthur Y.,Orru, Romano V. A.,Ruijter, Eelco,Hulme, Christopher
, p. 6132 - 6135 (2017)
Herein, a two-step MCR-oxidation methodology accessing decorated 2° α-ketoamides and α-ketotetrazoles is described via a catalytic copper(i)-mediated C-N oxidation/acidic hydrolysis of Ugi-three-component and Ugi-azide reaction products. The ability to in
Synthesis method of alpha-ketoamide compound
-
Paragraph 0103-0109, (2020/12/09)
The invention discloses a synthesis method of an alpha-ketoamide compound. The preparation method comprises the following steps of: taking an isocyanate compound as shown in a formula I and a benzoylformic acid compound as shown in a formula II as raw mat
Visible-light-mediated metal-free decarboxylative acylations of isocyanides with α-oxocarboxylic acids and water leading to α-ketoamides
Lv, Yufen,Bao, Pengli,Yue, Huilan,Li, Jiang-Sheng,Wei, Wei
supporting information, p. 6051 - 6055 (2019/11/20)
An efficient visible-light-promoted approach for preparing α-ketoamides from α-oxocarboxylic acids, isocyanides and water is disclosed. The present transformation could be achieved under mild and metal-free conditions through a sequence of decarboxylation
