21016-47-7Relevant articles and documents
Asymmetric dihydroxylation of β,γ-unsaturated carboxylic esters with trisubstituted C=C bonds - Enantioselective syntheses of trisubstituted γ-butyrolactones
Kapferer, Tobias,Brueckner, Reinhard
, p. 2119 - 2133 (2007/10/03)
β,γ-Unsaturated esters with stereodefined trisubstitued C=C double bonds were prepared by the Arndt-Eistert homologation of α,β-unsaturated carboxyl halides, by two-step methoxycarbonylation of allylbarium reagents, by deconjugation of α,β-unsaturated esters, and by Horner-Wadsworth-Emmons variants of the Stobbe condensation. Sharpless asymmetric dihydroxylation of the β,γ-unsaturated esters, followed by spontaneous cyclization, afforded β-hydroxy-γ-lactones in moderate to good yields and with enantiomeric excesses of up to 97 %. Similarly, tetrahydroxy-γ-lactones were obtained from diunsaturated esters; these lactones were converted into a bislactone and an unsaturated β-hydroxy γ-lactone. Wiley-VCH Verlag GmbH & Co. KGaA, 2006.
1,3-Dimethyl 2-oxo 1,3,2-diazaphospholidine precursor of (Z) α,β-unsaturated esters
Patois,Savignac
, p. 1317 - 1320 (2007/10/02)
α,β-Unsaturated esters of (Z) geometry are selectively obtained from cyclic phosphonocarboxylates derived from N,N'-dimethylethylenediamine.
A Stereoselective, Two-Step Preparation of α-Alkyl-α,β-unsaturated Esters
Larson, Gerald L.,Fernandez de Kaifer, Carmen,Seda, Rosa,Torres, Luz E.,Ramirez, J. Roberto
, p. 3385 - 3386 (2007/10/02)
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