2104-81-6

Basic information

• Product Name: 6-(4-chlorophenyl)-2,2-dimethylpiperidin-4-one
• Synonyms: 4-piperidinone, 6-(4-chlorophenyl)-2,2-dimethyl-; 6-(4-Chlorophenyl)-2,2-dimethylpiperidin-4-one
• CAS NO: 2104-81-6
• Molecular Formula: C₁₃H₁₆ClNO
• Molecular Weight: 237.7252
• Mol File: 2104-81-6.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 343.5°C at 760 mmHg
• Flash Point: 161.5°C
• Density: 1.113g/cm³
• Vapor Pressure: 7.03E-05mmHg at 25°C
• Refractive Index: 1.522
• CAS DataBase Reference: 6-(4-chlorophenyl)-2,2-dimethylpiperidin-4-one(CAS DataBase Reference)
• NIST Chemistry Reference: 6-(4-chlorophenyl)-2,2-dimethylpiperidin-4-one(2104-81-6)
• EPA Substance Registry System: 6-(4-chlorophenyl)-2,2-dimethylpiperidin-4-one(2104-81-6)

Safety Data

• Hazardous Substances Data: 2104-81-6(Hazardous Substances Data)

Upstream product

• 104-88-1 4-chlorobenzaldehyde 
• 67-64-1 acetone 

Relevant articles and documents

Highly efficient chemoselective construction of 2,2-dimethyl-6-substituted 4-piperidones via multi-component tandem Mannich reaction in ionic liquids

The room temperature ionic liquid [bmim][PF6] has been demonstrated to be an efficient and recyclable medium for highly chemoselective synthesis of 2,2-dimethyl-6-substituted 4-piperidones via a l-proline catalyzed tandem Mannich reaction of ammonia, aldehydes and acetone, and good yields were achieved for aryl and alkyl aldehydes.