210426-43-0 Usage
Indole derivative
Yes
Presence of bromine substitution
Yes (at the phenyl group)
Potential applications
Medicinal chemistry research, drug discovery and development, study of biological effects of indole derivatives
+ Appearance
Not specified in the material
+ Solubility
Not specified in the material
+ Melting point
Not specified in the material
+ Boiling point
Not specified in the material
+ Stability
Not specified in the material
+ Reactivity
Not specified in the material
Biological activity
Not specified in the material
Pharmacokinetic properties
Altered by bromine substitution, but not specified in the material
Synthesis
Not specified in the material
Check Digit Verification of cas no
The CAS Registry Mumber 210426-43-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,1,0,4,2 and 6 respectively; the second part has 2 digits, 4 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 210426-43:
(8*2)+(7*1)+(6*0)+(5*4)+(4*2)+(3*6)+(2*4)+(1*3)=80
80 % 10 = 0
So 210426-43-0 is a valid CAS Registry Number.
210426-43-0Relevant articles and documents
Analogues and derivatives of oncrasin-1, a novel inhibitor of the C-terminal domain of RNA polymerase II and their antitumor activities
Wu, Shuhong,Wang, Li,Guo, Wei,Liu, Xiaoying,Liu, Jinsong,Wei, Xiaoli,Fang, Bingliang
experimental part, p. 2668 - 2679 (2011/06/27)
To optimize the antitumor activity of oncrasin-1, a small molecule RNA polymerase II inhibitor, we evaluated 69 oncrasin-1 analogues for their cytotoxic activity against normal human epithelial cells and K-Ras mutant tumor cells. About 40 of those compoun