21057-39-6 Usage
Description
1-(CHLOROACETYL)-4-(2-METHOXYPHENYL)PIPERAZINE HYDROCHLORIDE is a chemical compound belonging to the piperazine derivative class, characterized by the presence of a chloroacetyl group and a methoxyphenyl group. These structural features contribute to its binding affinity and pharmacological activity, making it a significant compound in the pharmaceutical industry.
Uses
Used in Pharmaceutical Industry:
1-(CHLOROACETYL)-4-(2-METHOXYPHENYL)PIPERAZINE HYDROCHLORIDE is used as a serotonin receptor antagonist for the treatment of various neurological and psychiatric disorders. Its action on serotonin pathways makes it a potential candidate for addressing conditions related to serotonin dysregulation.
1-(CHLOROACETYL)-4-(2-METHOXYPHENYL)PIPERAZINE HYDROCHLORIDE is also used as a valuable tool in neuroscience research and drug development. 1-(CHLOROACETYL)-4-(2-METHOXYPHENYL)PIPERAZINE HYDROCHLORIDE's ability to modulate serotonin pathways provides insights into the underlying mechanisms of neurological and psychiatric disorders, aiding in the creation of novel therapeutic strategies.
The hydrochloride salt form of this compound is commonly utilized due to its improved solubility and stability, which enhances its pharmaceutical applications and effectiveness in treatment.
Check Digit Verification of cas no
The CAS Registry Mumber 21057-39-6 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,1,0,5 and 7 respectively; the second part has 2 digits, 3 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 21057-39:
(7*2)+(6*1)+(5*0)+(4*5)+(3*7)+(2*3)+(1*9)=76
76 % 10 = 6
So 21057-39-6 is a valid CAS Registry Number.
InChI:InChI=1/C13H17ClN2O2/c1-18-12-5-3-2-4-11(12)15-6-8-16(9-7-15)13(17)10-14/h2-5H,6-10H2,1H3
21057-39-6Relevant articles and documents
A new n-substituted 1h-isoindole-1,3(2h)-dione derivative— synthesis, structure and affinity for cyclooxygenase based on in vitro studies and molecular docking
Szkatu?a, Dominika,Krzy?ak, Edward,Stanowska, Paulina,Duda, Magdalena,Wiatrak, Benita
, (2021/07/19)
Isoindoline-1,3-dione derivatives constitute an important group of medicinal substances. In this study, nine new 1H-isoindole-1,3(2H)-dione derivatives and five potential pharmacophores were obtained in good yield (47.24–92.91%). The structure of the new
Synthesis and in vivo Anti-inflammatory Evaluation of Piperazine Derivatives Containing 1,4-Benzodioxan Moiety
Liu, Zhi-Ping,Gong, Chang-Da,Xie, Long-Yan,Du, Xiu-Li,Li, Yang,Qin, Jie
, p. 421 - 426 (2019/07/12)
Six piperazine derivatives 6a–f containing 1,4-benzodioxan moiety have been synthesized and characterized by 1H NMR, ESI-MS and elemental analysis. The structure of 6d was further confirmed by single crystal X-ray diffraction. All these novel c
Design, synthesis and biological profiling of aryl piperazine based scaffolds for the management of androgen sensitive prostatic disorders
Gupta, Sonal,Pandey, Deepti,Mandalapu, Dhanaraju,Bala, Veenu,Sharma, Vikas,Shukla, Mahendra,Yadav, Santosh K.,Singh, Nidhi,Jaiswal, Swati,Maikhuri, Jagdamba P.,Lal, Jawahar,Siddiqi, Mohammad I.,Gupta, Gopal,Sharma, Vishnu L.
supporting information, p. 2111 - 2121 (2016/11/18)
In the quest for novel scaffolds for the management of androgen sensitive prostatic disorders like prostate cancer and benign prostatic hyperplasia, a series of twenty-six aryl/heteroaryl piperazine derivatives have been described. Three compounds, 8a, 8c
