210691-38-6

Basic information

• Product Name: 1-(trifluoroacetyl)indoline-5-sulfonyl chloride
• Synonyms: 1-(trifluoroacetyl)indoline-5-sulfonyl chloride;1-(2,2,2-trifluoroacetyl)indoline-5-sulfonyl chloride;1H-Indole-5-sulfonyl chloride, 2,3-dihydro-1-(2,2,2-trifluoroacetyl)-;1-(2,2,2-Trifluoro-acetyl)-2,3-dihydro-1H-indole-5-sulfonyl chloride
• CAS NO: 210691-38-6
• Molecular Formula: C₁₀H₇ClF₃NO₃S
• Molecular Weight: 313.68
• Mol File: 210691-38-6.mol
• Article Data: 9

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 1-(trifluoroacetyl)indoline-5-sulfonyl chloride(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(trifluoroacetyl)indoline-5-sulfonyl chloride(210691-38-6)
• EPA Substance Registry System: 1-(trifluoroacetyl)indoline-5-sulfonyl chloride(210691-38-6)

Safety Data

• Hazardous Substances Data: 210691-38-6(Hazardous Substances Data)

Usage

General Description

1-(trifluoroacetyl)indoline-5-sulfonyl chloride is a chemical compound with the molecular formula C10H7ClF3NO3S. It is a sulfonyl chloride derivative with a trifluoroacetyl group attached to an indoline ring. 1-(trifluoroacetyl)indoline-5-sulfonyl chloride is commonly used as a building block in organic synthesis, particularly in the development of pharmaceuticals and agrochemicals. It is a versatile reagent in the preparation of various indoline-based compounds and is known for its potent reactivity and stability. Additionally, it has been studied for its potential applications in medicinal chemistry, with the potential for targeting biological pathways and enzyme inhibition.

Upstream product

• 90732-28-8 2,2,2-trifluoro-1-(indolin-1-yl)ethan-1-one 
• 7790-94-5 chlorosulfonic acid 
• 496-15-1 1-indoline 

Downstream Products

• 519148-72-2 5-(4-methyl-piperazine-1-sulfonyl)-1H-indole 
• 519148-73-3 5-(4-methyl-piperazine-1-sulfonyl)-indole-1-carboxylic acid tert-butyl ester 
• 519148-74-4 C₁₈H₂₆BN₃O₆S 

Relevant articles and documents

Discovery and Characterization of CD12681, a Potent RORγ Inverse Agonist, Preclinical Candidate for the Topical Treatment of Psoriasis

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A class of sulfonamide carbonic anhydrase inhibitors with neuropathic pain modulating effects

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