210697-27-1

Basic information

• Product Name: 3-Pyridinecarboxylic acid, 5-bromo-6-(dimethylamino)-2-methoxy-, methyl ester
• CAS NO: 210697-27-1
• Molecular Formula: C10H13BrN2O3
• Mol File: 210697-27-1.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 3-Pyridinecarboxylic acid, 5-bromo-6-(dimethylamino)-2-methoxy-, methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 3-Pyridinecarboxylic acid, 5-bromo-6-(dimethylamino)-2-methoxy-, methyl ester(210697-27-1)
• EPA Substance Registry System: 3-Pyridinecarboxylic acid, 5-bromo-6-(dimethylamino)-2-methoxy-, methyl ester(210697-27-1)

Safety Data

• Hazardous Substances Data: 210697-27-1(Hazardous Substances Data)

Upstream product

• 210697-20-4 methyl 6-dimethylamino-2-fluoropyridine-3-carboxylate 
• 171178-50-0 2,6-difluoronicotinic acid 

Relevant articles and documents

Synthesis of N-(1-ethyl-4-methylhexahydro-1,4-diazepin-6- yl)nicotinamides and their affinities for 5-HT3 and dopamine D2 receptors

A series of N-(1-ethyl-4-methylhexahydro-1,4-diazepin-6-yl)nicotinamide derivatives were prepared and evaluated for their binding to 5-HT3 and dopamine D2 receptors. Among them, the 5-bromo-2-methoxy-6- methylaminonicotinamide 16 and its (R)-isomer were found to have potent affinities for both receptors. The affinities of (R)-16 for 5-HT3 and dopamine D2 receptors are approximately 3-fold higher than those of the corresponding benzamide (R)-1 (IC50: 1.1 and 12 nM vs. 2.9 and 35 nM, respectively).