210701-09-0Relevant articles and documents
Allylic substitution of meso-1,4-diacetoxycycloalkenes in water with an amphiphilic resin-supported chiral palladium complex
Uozumi, Yasuhiro,Takenaka, Hiroe,Suzuka, Toshimasa
experimental part, p. 1557 - 1561 (2009/04/07)
Asymmetric π-allylic substitution of meso-1,4-diacet-oxycyclopentene and meso-1,4-diacetoxycyclohexene with various nucleophiles was performed with an amphiphilic polystyrene-polyethylene glycol) (PS-PEG) resin-supported chiral imidazoin-dolephosphine-palladium complex in water as a single reaction medium under heterogeneous conditions to give the corresponding 1-acetoxy-4-substituted cycloalkenes with up to 99% ee.
Chemoenzymatic synthesis of a versatile cyclopentenone: (+)-(3aS,6aS)-2,2-dimethyl-3aβ,6aβ-dihydro-4H-cyclopenta-1,3-dioxol- 4-one
Biadatti, Thibaud,Esker, John L.,Johnson, Carl R.
, p. 2313 - 2320 (2007/10/03)
The title cyclopentenone has been prepared by enzymatic resolution of cis-4-phenyloxy- and cis-4-(4-methoxyphenyloxy)-cyclopent-2-en-1-ol in isopropenyl acetate using Pseudomonas cepacia lipase. The use of a 4-methoxyphenyloxy-alcohol intermediate enabled the use of both enzymatically resolved enantiomers in the synthesis of the desired (+)-enone.
