21078-03-5

Basic information

• Product Name: Benzene, 1,3-dimethyl-2-(2-propynyloxy)-
• CAS NO: 21078-03-5
• Molecular Formula: C11H12O
• Molecular Weight: 160.216
• Mol File: 21078-03-5.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: Benzene, 1,3-dimethyl-2-(2-propynyloxy)-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzene, 1,3-dimethyl-2-(2-propynyloxy)-(21078-03-5)
• EPA Substance Registry System: Benzene, 1,3-dimethyl-2-(2-propynyloxy)-(21078-03-5)

Safety Data

• Hazardous Substances Data: 21078-03-5(Hazardous Substances Data)

Upstream product

• 576-26-1 2.6-dimethylphenol 
• 106-96-7 propargyl bromide 

Relevant articles and documents

A short, vinyl radical cyclisation approach to (±))-2-pupukeanone

Addition of tri-n-butyltin radical to a 5-(prop-2-ynyl)bicyclo [2.2.2]oct-2-ene followed by 5-exo-trig cyclisation of the resulting vinyl radical furnishes an isotwistane, providing a short route to the sesquiterpenes, pupukeananes 4 and 2.

Method for synthesizing mexiletine chloride

The invention discloses a method for synthesizing mexiletine chloride, wherein a reaction system takes 2,6-xylenol as a starting material to synthesize a corresponding target product. In the reaction,a transition metal gold complex and a ruthenium complex are used for catalysis, compared with the previous method for synthesizing mexiletine chloride, no alkali is added during a reaction process, no by-products are produced, the reaction atom economy is high, and the reaction conditions are mild. Therefore, the method has broad development prospects.

Formal total synthesis of 2-pupukeanone via radical mediated cyclisation of an enyne

Diels-Alder reaction of the dienone 12, obtained by C-alkylation of sodium 2,6-dimethylphenoxide, with acrylonitrile and phenyl vinyl sulfones generate the enynes 14 and 17. Tributyltin radical addition to the terminal acetylene in 14 and 17 lead to the v