210888-94-1Relevant articles and documents
Indole arylation studies directed towards the synthesis of simplified eastern subunits of Chloropeptin and Kistamycin
Carbonnelle, Annie-Claude,Gonzalez Zamora, Eduardo,Beugelmans, Rene,Roussi, Georges
, p. 4467 - 4470 (1998)
Aryl indoles which are building blocks for the synthesis of simplified analogues of macropolypeptides containing an endo carbon-carbon bond are obtained by Suzuki Pd-catalyzed cross coupling reactions involving either haloindoles or indole boronic acids a
Synthesis of highly functionalized triarylbismuthines by functional group manipulation and use in palladium- and copper-catalyzed arylation reactions
Hébert, Martin,Petiot, Pauline,Benoit, Emeline,Dansereau, Julien,Ahmad, Tabinda,Le Roch, Adrien,Ottenwaelder, Xavier,Gagnon, Alexandre
, p. 5401 - 5416 (2016/07/13)
Organobismuthines are an attractive class of organometallic reagents that can be accessed from inexpensive and nontoxic bismuth salts. Triarylbismuthines are particularly interesting due to their air and moisture stability and high functional group tolerance. We report herein a detailed study on the preparation of highly functionalized triarylbismuth reagents by triple functional group manipulation and their use in palladium- and copper-catalyzed C-, N-, and O-arylation reactions.
SUBSTITUTED BIS ARYL AND HETEROARYL COMPOUNDS AS SELECTIVE 5HT2A ANTAGONISTS
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Page/Page column 44-45, (2008/06/13)
The present invention relates to a series of substituted bis aryl and heteroaryl compounds of formula (I): Wherein X, Y, Z, A, B, D, Ar, R 1 and R2 are as defined herein. The compounds of this invention are selective 5HT2A antagonists, and are therefore, useful in treating a variety of diseases including but not limited to a wide variety of sleep disorders as disclosed and claimed herein.