2109-12-8

Basic information

• Product Name: 2,4,6-triiodo-m-cresol
• Synonyms: 2,4,6-triiodo-m-cresol;2,4,6-Triiodo-3-methylphenol
• CAS NO: 2109-12-8
• Molecular Formula: C₇H₅I₃O
• Molecular Weight: 485.82741
• EINECS: 218-294-6
• Mol File: 2109-12-8.mol
• Article Data: 5

Chemical Properties

• Boiling Point: 328.2°C at 760 mmHg
• Flash Point: 152.3°C
• Appearance: /
• Density: 2.851g/cm³
• Vapor Pressure: 0.000101mmHg at 25°C
• Refractive Index: 1.783
• CAS DataBase Reference: 2,4,6-triiodo-m-cresol(CAS DataBase Reference)
• NIST Chemistry Reference: 2,4,6-triiodo-m-cresol(2109-12-8)
• EPA Substance Registry System: 2,4,6-triiodo-m-cresol(2109-12-8)

Safety Data

• Hazardous Substances Data: 2109-12-8(Hazardous Substances Data)

Usage

General Description

2,4,6-triiodo-m-cresol is a chemical compound that is commonly used as an antiseptic and disinfectant. It is a derivative of phenol and belongs to the group of triiodo-m-cresol compounds, which are known for their antibacterial and antifungal properties. This chemical is often used in various medical and healthcare products, including skin ointments, soaps, and surgical scrubs, due to its ability to effectively eliminate harmful microorganisms. Additionally, 2,4,6-triiodo-m-cresol is also employed in industrial and agricultural settings as a preservative and biocide. However, it should be used with caution as it can be toxic if ingested or absorbed through the skin in large amounts, and exposure to this compound may cause irritation to the skin and eyes.

InChI:InChI=1/C7H5I3O/c1-3-4(8)2-5(9)7(11)6(3)10/h2,11H,1H3

Upstream product

• 108-39-4 3-methyl-phenol 
• 67-56-1 methanol 
• 7664-41-7 ammonia 
• 7732-18-5 water 
• 7553-56-2 iodine 

Downstream Products

• 139220-41-0 5--4-<2-(trimethylsilyl)eth-1-oxy>-2(5H)furanone 
• 124311-26-8 (3-methyl-2,4,6-triiodophenyl)-2,2,3,4,4-pentafluoro-3,4-dibromo-butyrate 

Relevant articles and documents

Gas-Chromatographic identifi cation of products formed in iodination of methyl phenols by retention indices

Iodination reaction followed by conversion of iodine-substituted methylphenols to the corresponding trifl uoroacetates was suggested for improving the sensitivity of the gas-chromatographic determination of phenol and its methyl-substituted derivatives (al isomers of mono- and diethylphenols, 2,3,5-, 2,3,6-, and 3,4,5-trimethylphenols) in aqueous media. Acylation products of iodo methylphenols (104 compounds) were identifi ed by linear-logarithmic retention indices on a standard nonpolar polydimethylsiloxane stationary phase, and the pattern of their variation with the number and nature of substituents were characterized. A procedure for identifi cation of methyl-substituted phenols in water in their gas-chromatographic determination with an electron-capture detector was developed. Pleiades Publishing, Ltd., 2012.

Synthesis, characterization, X-ray structural analysis, and iodination ability of benzyl(triphenyl)phosphonium dichloroiodate

Benzyl(triphenyl)phosphonium dichloroiodate (BTPPICl2), BnPh3P+(ICl2)-, is easily synthesized in a nearly quantitative yield by the addition of BnPh 3P+Cl- to a CH2Cl2 solution of iodine monochloride (ICl). BnPh3P+Cl - can be prepared by the reaction of Ph3P and BnCl. The compound was characterized by physicochemical and spectroscopic methods (elemental analysis, FT-IR, and 1H-NMR). The use of phosphonium counterion improves the quality of the BTPPICl2 crystals. BTPPICl2 crystallizes in the monoclinic system, and its crystal and molecular structure has been determined at 100(1) K by X-ray diffraction. The structure was solved by the direct method and had refined R value of 0.0637 for 699 reflections (I>2σ(I)), space group P21/n with a=12.4700(3), b=13.2196(3), c=14.4580(3) A, β=102.6340(10)°, V=2325.67(9) A3, and Z=4. The I-atom is coordinated by two Cl-atoms as ligands in a linear geometry. This compound is a versatile reagent for the efficient and selective iodination of organic substrates, in particular of aromatic phenols to the corresponding iodo compounds, under mild conditions. To assess the generality of method, a wide variety of phenols with electron-donating and electron-withdrawing substituents were studied. BTPPICl2 is a mild iodination reagent, which offers a new avenue for an expeditious iodination of phenols. The inexpensive, relatively non-toxic reagent, and mild conditions are the positive features of the procedure and reagent. Copyright

Potential X ray contrast agents. II. Synthesis of some basic derivatives of 3,5 diiodo 4 pyridone

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