210964-81-1Relevant articles and documents
New bis(oxazoline) ligands with secondary binding sites for the asymmetric cyclopropanation of furans
Schinnerl, Marina,Boehm, Claudius,Seitz, Michael,Reiser, Oliver
, p. 765 - 771 (2003)
The diastereo- and enantioselective cyclopropanation of furans was achieved in up to 91% ee using a new set of chiral bis(oxazoline) ligands that are able to use secondary binding sites to enhance selectivity. In contrast, with substrates such as styrene
New applications of bis(oxazoline) ligands in catalysis: Asymmetric 1,2-and 1,4-addition of ZnR2 to carbonyl compounds
Schinnerl, Marina,Seitz, Michael,Kaiser, Anja,Reiser, Oliver
, p. 4259 - 4262 (2007/10/03)
(Matrix Presented) The enantioselective addition of ZnR2 to aldehydes (1,2) and cyclic enones (1,4) was accomplished using bis(oxazolines) as chiral ligands. The requirement for hydroxymethylene side chains in the ligands strongly suggests that bimetallic catalysts are decisive for high enantiocontrol in these additions.