2111-71-9 Usage
Description
(E)-1-(6,6-dimethylbicyclo[3.1.1]hept-2-en-2-yl)-N-hydroxymethanimine is a bicyclic chemical compound with the molecular formula C11H17NO. It features a hydroxymethanimine group and a bicyclo[3.1.1]heptene moiety, with a trans configuration. This colorless liquid at room temperature is utilized in organic synthesis and has potential applications in coordination chemistry due to its ability to act as a ligand. Additionally, it has shown promise in medicinal properties, such as anti-inflammatory and neuroprotective effects, making it a compound of interest for further research and development.
Uses
Used in Organic Synthesis:
(E)-1-(6,6-dimethylbicyclo[3.1.1]hept-2-en-2-yl)-N-hydroxymethanimine is used as a key intermediate in the synthesis of various organic compounds. Its unique bicyclic structure and functional groups make it a valuable building block for creating complex molecules with specific properties and applications.
Used as a Ligand in Coordination Chemistry:
In coordination chemistry, (E)-1-(6,6-dimethylbicyclo[3.1.1]hept-2-en-2-yl)-N-hydroxymethanimine is used as a ligand to form coordination complexes with metal ions. These complexes can exhibit unique chemical and physical properties, which can be exploited in various applications, such as catalysis, sensing, and materials science.
Used in Medicinal Chemistry:
(E)-1-(6,6-dimethylbicyclo[3.1.1]hept-2-en-2-yl)-N-hydroxymethanimine is used as a starting material or a structural component in the development of new pharmaceuticals. Its demonstrated anti-inflammatory and neuroprotective effects make it a promising candidate for the treatment of various diseases and conditions, including inflammation-related disorders and neurodegenerative diseases.
Used in Pharmaceutical Research and Development:
In the pharmaceutical industry, (E)-1-(6,6-dimethylbicyclo[3.1.1]hept-2-en-2-yl)-N-hydroxymethanimine is used as a molecule of interest for further research and development. Its potential medicinal properties, along with its unique chemical structure, make it a valuable compound for exploring new therapeutic approaches and developing innovative drugs.
Check Digit Verification of cas no
The CAS Registry Mumber 2111-71-9 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 2,1,1 and 1 respectively; the second part has 2 digits, 7 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 2111-71:
(6*2)+(5*1)+(4*1)+(3*1)+(2*7)+(1*1)=39
39 % 10 = 9
So 2111-71-9 is a valid CAS Registry Number.
2111-71-9Relevant articles and documents
Ruthenium-catalyzed rearrangement of aldoximes to primary amides in water
Garcia-Alvarez, Rocio,Diaz-Alvarez, Alba E.,Borge, Javier,Crochet, Pascale,Cadierno, Victorio
, p. 6482 - 6490 (2012/10/30)
The rearrangement of aldoximes to primary amides has been studied using the readily available arene-ruthenium(II) complex [RuCl2(η 6-C6Me6){P(NMe2)3}] (5 mol %) as catalyst. Reactions proceeded cleanly in pure water at 100 °C without the assistance of any cocatalyst, affording the desired amides in high yields (70-90%) after short reaction times (1-7 h). The process was operative with both aromatic, heteroaromatic, α,β-unsaturated, and aliphatic aldoximes and tolerated several functional groups. Reaction profiles and experiments using 18O-labeled water indicate that two different mechanisms are implicated in these transformations. In both of them, nitrile intermediates are initially formed by dehydration of the aldoximes. These intermediates are then hydrated to the corresponding amides by the action of a second molecule of aldoxime or water. A kinetic analysis of the rearrangement of benzaldoxime to benzamide is also discussed.
