21120-91-2 Usage
Description
1-Bromobenzocyclobutene is a colorless to pale yellow liquid that serves as a useful synthon in various chemical reactions. It is synthesized through the reaction of cycloheptatriene, bromoform, potassium carbonate, and 18-crown-6 at 140°C. 1-Bromobenzocyclobutene has significant applications in organometallic methodology.
Uses
Used in Organic Synthesis:
1-Bromobenzocyclobutene is used as a synthetic intermediate for the preparation of various organic compounds, including five-membered zirconacycles, benzocyclobutenol, and benzocyclobutenone. Its unique structure and reactivity make it a valuable building block in the synthesis of complex organic molecules.
Used in Pharmaceutical Industry:
1-Bromobenzocyclobutene is used as a key intermediate in the synthesis of 2,3-dimethoxyprotoberberinium bromide, which is obtained through a reaction with 3,4-dihydro-6,7-dimethoxyisoquinoline. 1-Bromobenzocyclobutene has potential applications in the development of pharmaceuticals, particularly in the treatment of various diseases.
Used in Organometallic Methodology:
1-Bromobenzocyclobutene is used as a versatile reagent in organometallic chemistry, where it can be employed to form metal complexes and contribute to the development of new catalytic systems and materials. Its applications in this field are crucial for advancing the understanding of organometallic reactions and their potential applications in various industries.
Check Digit Verification of cas no
The CAS Registry Mumber 21120-91-2 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,1,1,2 and 0 respectively; the second part has 2 digits, 9 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 21120-91:
(7*2)+(6*1)+(5*1)+(4*2)+(3*0)+(2*9)+(1*1)=52
52 % 10 = 2
So 21120-91-2 is a valid CAS Registry Number.
InChI:InChI=1/C8H7Br/c9-8-5-6-3-1-2-4-7(6)8/h1-4,8H,5H2
21120-91-2Relevant articles and documents
Studies on the syntheses of heterocyclic compounds DXLV. An alternative synthesis of the protoberberine ring system
Kametani,Kato,Fukumoto
, p. 1043 - 1046 (1974)
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DENDRITIC MOLECULAR INTRACELLULAR TRANSPORTERS AND METHODS OF MAKING AND USING SAME
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Page/Page column 104, (2010/11/30)
In accordance with the purpose(s) of the invention, as embodied and broadly described herein, the invention, in one aspect, relates to compounds comprising the structure: and at least one guanidinium residue, wherein m is zero or a positive integer. Also disclosed are methods of preparing the disclosed compounds. Also disclosed are methods of intracellular delivery comprising administering the disclosed compounds and compositions to a subject. Also disclosed are pharmaceutical compositions comprising a therapeutically effective amount of one or more compounds or compositions of the invention and a pharmaceutically acceptable carrier. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.
1-Bromobenzocyclobutene: A Convenient Entry into the Benzocyclobutene Ring System
DeCamp, Mark R.,Viscogliosi, Lori A.
, p. 3918 - 3920 (2007/10/02)
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