211488-49-2Relevant articles and documents
Synthesis of 1-(1H-imidazol-2-yl)ethane-1,2-diol derivatives: A novel class of protein kinase C inhibitors
Roehrle, Andreas N.,Schmidhammer, Helmut
, p. 1070 - 1076 (2007/10/03)
Compounds 6-13 were prepared starting from 1-(triphenlymethyl)-protected 1H-imidazoles 14 and 15 in several steps. Lithiation with BuLi in THF followed by reaction with (triphenylmethoxy)acetaldehyde (16) afforded 17 and 18, respectively. O-Methylation of