21160-87-2 Usage
Description
L-GLUTAMIC-15N ACID, also known as 15N-L-Glutamic acid (G596960), is a nitrogen-15 labeled form of L-Glutamic acid, an essential amino acid that serves as a vital neurotransmitter. It plays a significant role in long-term potentiation, which is crucial for learning and memory processes. Additionally, L-GLUTAMIC-15N ACID is an important molecule in cellular metabolism, contributing to the overall functioning of cells.
Uses
Used in Pharmaceutical Industry:
L-GLUTAMIC-15N ACID is used as a research compound for studying the role of glutamic acid in various physiological processes. Its application in this industry is primarily for understanding the mechanisms of neurotransmission, learning, and memory, as well as its involvement in cellular metabolism.
Used in Neuroscientific Research:
L-GLUTAMIC-15N ACID is used as a tracer in neuroscientific research to investigate the dynamics of glutamate neurotransmission. This helps researchers gain insights into the functioning of the nervous system and the role of glutamic acid in cognitive processes.
Used in Metabolic Studies:
L-GLUTAMIC-15N ACID is used as a metabolic tracer to study the role of glutamic acid in cellular metabolism. This application aids in understanding the metabolic pathways and the overall energy production within cells.
Used in Diagnostic Applications:
L-GLUTAMIC-15N ACID can be used in diagnostic applications to detect and monitor various neurological disorders related to neurotransmission dysfunction. Its use in this context can help in the early diagnosis and treatment of such conditions.
Used in Nutritional Supplements:
L-GLUTAMIC-15N ACID may be used as an ingredient in nutritional supplements designed to support cognitive function and overall brain health. Its role in learning and memory makes it a potential candidate for inclusion in such products.
Used in Agricultural Industry:
L-GLUTAMIC-15N ACID can be used in the agricultural industry as a component in animal feed to enhance cognitive function and overall health in livestock. Its role in neurotransmission and cellular metabolism can contribute to improved animal welfare and productivity.
Check Digit Verification of cas no
The CAS Registry Mumber 21160-87-2 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,1,1,6 and 0 respectively; the second part has 2 digits, 8 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 21160-87:
(7*2)+(6*1)+(5*1)+(4*6)+(3*0)+(2*8)+(1*7)=72
72 % 10 = 2
So 21160-87-2 is a valid CAS Registry Number.
21160-87-2Relevant articles and documents
Zintel et al.
, p. 411,412 (1969)
The 15N labelled L-glutamic acid: Experimental and computational NMR studies
Vulcu, Adriana,Berghian Grosan, Camelia,Chiriac, Maria,Almasan, Valer
experimental part, p. 667 - 674 (2012/04/23)
15N labelled L-glutamic acid is synthesized by the reductive amination of α-ketoglutarate, in the presence of glutamate dehydrogenase (GDH), nicotinamide adenine dinucleotide (NADH) as cofactor and 15NH4Cl as source of isotope 15N. The reaction mixture includes glucose dehydrogenase (GlcDH) and glucose, as electron donor, for NADH regeneration, too. We are also interested in the theoretical calculation of NMR parameters for this compound; the 13C chemical shifts and coupling constants were calculated by B3LYP (hybrid Becke 3 Lee Yang Parr) density functional method with 6-311+G(d, p) basis set. For chemical shifts and coupling constants prediction the GIAO (Gauge-Induced Atomic Orbital) approximation and the keyword NMR=spinspin respectively were used. Comparison between the experimental and theoretical results indicates that DFT/B3LYP/6-311+G(d, p) method is in good agreement with the experimental data.
