21164-16-9

Basic information

• Product Name: bis-[2-(4-nitro-benzoylamino)-phenyl]-disulfide
• CAS NO: 21164-16-9
• Molecular Weight: 546.584
• Mol File: 21164-16-9.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: bis-[2-(4-nitro-benzoylamino)-phenyl]-disulfide(CAS DataBase Reference)
• NIST Chemistry Reference: bis-[2-(4-nitro-benzoylamino)-phenyl]-disulfide(21164-16-9)
• EPA Substance Registry System: bis-[2-(4-nitro-benzoylamino)-phenyl]-disulfide(21164-16-9)

Safety Data

• Hazardous Substances Data: 21164-16-9(Hazardous Substances Data)

Upstream product

• 122-04-3 4-nitro-benzoyl chloride 
• 1141-88-4 2-Aminophenyl disulfide 
• 98370-54-8 zinc 2-aminobenzenethiolate 
• 137-07-5 2-amino-benzenethiol 
• 62-23-7 4-nitro-benzoic acid 

Downstream Products

• 6278-73-5 2-(4-aminophenyl)benzothiazole 

Relevant articles and documents

Solid phase synthesis of benzothiazolyl compounds

2-Aminobenzenethiol, bound through its thiol function to the 2-chlorotrityl (Clt)-, trityl (Trt)-, 4-methyltrityl (Mtt)- and 4-methoxytrityl (Mmt)-resins, was acylated at the amino-function by aliphatic and aromatic acids. The obtained 2-N-acyl-aminobenzenethiols were cleaved from the resin by treatment with trifluoroacetic acid solutions in dichloromethane. The 2-N-acyl-aminobenzenethiols released from the resin were cyclised to the corresponding 2-substituted benzothiazoles, by standing in a solution of dithiothreitol in DMF or methanol for 1-3 h at room temperature.